ABSTRACT
UNLABELLED: Rhabdomyosarcoma (RMS) is a malignant tumor of soft tissues, more common in childhood, mainly located in the head and neck. It presents varied clinical and biological behavior and requires individualized management. AIM: To describe information on patients with head and neck RMS diagnosed and treated in a hospital, and to compare them to results in the literature. STUDY DESIGN: Descriptive and retrospective. MATERIALS AND METHODS: A retrospective analysis of data from 24 patients with head and neck rhabdomyosarcoma diagnosed and treated in a hospital from 1994 to 2008. RESULTS: The mean age was 7.79 years. According to gender, 54.17 % were males and 45.83 % were female. All patients underwent chemotherapy (CT), 62.5% of them also underwent radiotherapy (RT) and 16.67% were submitted to surgery. Of the 24 patients, 8 (33.3%) died, 6 (25%) were found free of neoplasia and 2 (8.3%) experienced tumor recurrence. CONCLUSION: The RMS of the head and neck often presents with nonspecific symptoms. Individualized multimodal therapy should be performed for these patients, including surgery, chemotherapy and radiotherapy.
Subject(s)
Head and Neck Neoplasms , Rhabdomyosarcoma , Adolescent , Adult , Child , Child, Preschool , Combined Modality Therapy/methods , Disease-Free Survival , Female , Head and Neck Neoplasms/diagnosis , Head and Neck Neoplasms/mortality , Head and Neck Neoplasms/therapy , Humans , Infant , Infant, Newborn , Male , Middle Aged , Retrospective Studies , Rhabdomyosarcoma/diagnosis , Rhabdomyosarcoma/mortality , Rhabdomyosarcoma/therapy , Young AdultABSTRACT
O rabdomiossarcoma (RMS) é o tumor maligno de partes moles mais comum na infância, localizando-se principalmente na cabeça e pescoço. Apresenta comportamento clínico-biológico variado, devendo receber terapia individualizada. OBJETIVO: Descrever os dados de pacientes portadores de RMS de cabeça e pescoço diagnosticados e tratados em um hospital comparando-os aos da literatura. Forma de Estudo: Descritivo retrospectivo. MATERIAL E MÉTODO: Análise retrospectiva de dados de prontuários de 24 pacientes portadores de RMS de cabeça e pescoço diagnosticados e tratados em um hospital no período de 1994 a 2008. RESULTADOS: A média de idade foi de 7,79 anos. Quanto ao sexo, encontramos 54,17 por cento do sexo masculino e 45,83 por cento do sexo feminino. Todos os pacientes foram submetidos a quimioterapia (QT), sendo que 62,5 por cento destes também realizaram radioterapia (RT) e 16,67 por cento foram submetidos a cirurgia. Dos 24 pacientes, 8 (33,3 por cento) foram a óbito, 6 (25 por cento) encontravam-se livres de neoplasia e 2 ( 8,3 por cento) apresentaram recidiva do tumor. CONCLUSÃO: O RMS de cabeça e pescoço frequentemente se apresenta com sintomas inespecíficos. Terapia multimodal individualizada deve ser realizada, incluindo cirurgia, quimioterapia e radioterapia.
Rhabdomyosarcoma (RMS) is a malignant tumor of soft tissues, more common in childhood, mainly located in the head and neck. It presents varied clinical and biological behavior and requires individualized management. AIM: To describe information on patients with head and neck RMS diagnosed and treated in a hospital, and to compare them to results in the literature. Study design: Descriptive and retrospective. MATERIALS AND METHODS: A retrospective analysis of data from 24 patients with head and neck rhabdomyosarcoma diagnosed and treated in a hospital from 1994 to 2008. RESULTS: The mean age was 7.79 years. According to gender, 54.17 percent were males and 45.83 percent were female. All patients underwent chemotherapy (CT), 62.5 percent of them also underwent radiotherapy (RT) and 16.67 percent were submitted to surgery. Of the 24 patients, 8 (33.3 percent) died, 6 (25 percent) were found free of neoplasia and 2 (8.3 percent) experienced tumor recurrence. CONCLUSION: The RMS of the head and neck often presents with nonspecific symptoms. Individualized multimodal therapy should be performed for these patients, including surgery, chemotherapy and radiotherapy.
