ABSTRACT
Tuberculosis (TB) is a lung disease caused by Mycobacterium tuberculosis. The interaction between the bacillus and the host may lead to a protective cellular immune response. In the present study, we propose the "in vitro" evaluation of this cellular immune response in patients with tuberculosis before and after chemotherapic treatment. Eleven patients with TB and 9 asymptomatic subjects with tuberculin skin test negative (TST-) (purified protein derivative (PPD) Subject(s)
Immunophenotyping
, Leukocytes, Mononuclear/immunology
, Mycobacterium tuberculosis/immunology
, Tuberculosis, Pulmonary/immunology
, Adolescent
, Adult
, Antitubercular Agents/therapeutic use
, B-Lymphocytes/immunology
, CD4-Positive T-Lymphocytes/immunology
, CD8-Positive T-Lymphocytes/immunology
, Case-Control Studies
, Female
, Humans
, Interferon-gamma/immunology
, Killer Cells, Natural/immunology
, Macrophages/immunology
, Male
, Middle Aged
, T-Lymphocyte Subsets
, T-Lymphocytes, Regulatory/immunology
, Tuberculin Test
, Tuberculosis, Pulmonary/drug therapy
