ABSTRACT
PURPOSE: There is limited literature on the ocular manifestations in patients with psoriasis. Therefore, this study aimed to identify the prevalence of and factors associated with ocular manifestations in adults with psoriasis. METHODS: This cross-sectional study included Brazilian adults with psoriasis. The dermatological evaluation included diagnosis, clinical form, Psoriasis Area and Severity Index (PASI) measurement, and location of the lesions. Patients underwent a full ophthalmological examination, including the Schirmer I test, Rose Bengala staining, and tear breakup time tests. The results were analyzed using chi-square and Pearson's linear correlation tests. RESULTS: Of the 130 patients assessed, 118 (90.8%) exhibited ocular abnormalities, with meibomian gland dysfunction (MGD) being the most prevalent (59.2%), followed by dry eye disease (DED) (56.2%). A significant correlation was observed between MGD and PASI (p = 0.05), and between MGD and certain treatment modalities. DED was significantly associated with PASI (p < 0.05). Concurrent use of acitretin was identified as an independent predictor of MGD (odds ratio [OR] = 3.5, p < 0.05), whereas PASI was a protective factor against DED (OR = 0.39, p < 0.01). CONCLUSION: Given the high prevalence of eye disease among individuals with psoriasis, routine ophthalmological assessments are recommended to prevent possible ocular complications.
Subject(s)
Dry Eye Syndromes , Psoriasis , Humans , Cross-Sectional Studies , Male , Psoriasis/epidemiology , Psoriasis/complications , Female , Brazil/epidemiology , Adult , Middle Aged , Prevalence , Dry Eye Syndromes/epidemiology , Dry Eye Syndromes/etiology , Dry Eye Syndromes/diagnosis , Meibomian Gland Dysfunction/epidemiology , Meibomian Gland Dysfunction/diagnosis , Meibomian Gland Dysfunction/etiology , Severity of Illness Index , Aged , Young AdultABSTRACT
This study aimed to determine the pars plana length in postmortem human eyes using advanced morphometric techniques and correlate demographics to ocular metrics such as age, sex, ethnicity, and axial length. Between February and July 2005, we conducted a cross-sectional observational study on 46 human cadaver eyes deemed unsuitable for transplant by the SBO Eye Bank. The morphometric analysis was performed on projected images using a surgical microscope and a video-microscopy system with a 20.5:1 correction factor. The pars plana length was measured three times per quadrant, with the final value being the mean of these measurements. Of the 46 eyes collected, 9 were unsuitable for the study due to technical constraints in conducting intraocular measurements. Overall, the average axial length was 25.20 mm. The average pars plana length was 3.8 mm in all quadrants, with no measurements below 2.8 mm or above 4.9 mm. There were no statistically significant variations across quadrants or with age, sex, axial length, or laterality. Accurately defining the pars plana dimensions is crucial for safely accessing the posterior segment of the eye and minimizing complications during intraocular procedures, such as intravitreal injections and vitreoretinal surgeries.
ABSTRACT
Five retinocytoma cases diagnosed over 75 months are reported. The mean age at diagnosis was 193.2 months. Two cases were unilateral, one was bilateral and two exhibited retinoblastoma in the fellow eye. Clinical and ophthalmoscopic aspects, genetical implications and the need of treatment and continuous follow-up of retinocytoma patients are discussed.
Subject(s)
Retinal Neoplasms/pathology , Retinoblastoma/pathology , Adult , Calcinosis/pathology , Child, Preschool , Female , Humans , Male , Retinal Neoplasms/therapy , Retinoblastoma/therapy , Young AdultABSTRACT
São apresentados dois casos de descolamento de coróide em olhos com endoftalmite submetidos a enucleação. O estudo anatomopatológico permitiu identificar a presença de tecido vascular e nervoso interpondo-se entre a esclera e coróide deslocada, como havia sido evidenciado pela ecografia.
Two cases of endophthalmitis with choroidal detachment submitted to enucleation are presented. The histopathologic study allowed the identification of vascular and nervous tissue between the choroid and sclera, as it was seen on ultrasound examination.
Subject(s)
Aged , Aged, 80 and over , Humans , Male , Choroid Diseases/pathology , Choroid Diseases , Endophthalmitis , Choroid/blood supply , Choroid/innervation , Endophthalmitis/complications , Endophthalmitis/surgery , Sclera/blood supply , Sclera/innervationABSTRACT
Relatamos cinco casos de retinocitoma diagnósticados em um período de 75 meses. A média de idade ao diagnóstico foi de 193,2 meses. Dois casos apresentavam tumor unilateral, um bilateral e dois exibiam retinoblastoma no olho contralateral. As características clínicas e oftalmoscópicas, as implicações genéticas e a necessidade de tratamento e acompanhamento contínuo dos pacientes com retinocitoma são discutidas.
Five retinocytoma cases diagnosed over 75 months are reported. The mean age at diagnosis was 193.2 months. Two cases were unilateral, one was bilateral and two exhibited retinoblastoma in the fellow eye. Clinical and ophthalmoscopic aspects, genetical implications and the need of treatment and continuous follow-up of retinocytoma patients are discussed.
Subject(s)
Adult , Child, Preschool , Female , Humans , Male , Young Adult , Retinal Neoplasms/pathology , Retinoblastoma/pathology , Calcinosis/pathology , Retinal Neoplasms/therapy , Retinoblastoma/therapy , Young AdultABSTRACT
Two cases of endophthalmitis with choroidal detachment submitted to enucleation are presented. The histopathologic study allowed the identification of vascular and nervous tissue between the choroid and sclera, as it was seen on ultrasound examination.
