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4.
Allergol. immunopatol ; 35(4): 130-135, jul. 2007. ilus
Article in En | IBECS | ID: ibc-055347

ABSTRACT

Background: Obesity and atopy are two increasingly important population health issues. Excess weight and obesity are potential risk factors for atopy (specifically asthma). Objective and methods: To determine the body mass index (BMI) in children with atopic disease compared with nonatopic children, and to determine whether obesity is associated to more severe disease. Children aged 5 to 16 years with diagnosed atopic disease that attended the Ambulatory Hospital Center where eligible as cases. Children aged 5 to 16 years without atopic disease from a school in the same geographic area were used as controls. Results: A total of 228 children where included in the analysis: 112 children with atopy (75.9 % asthma, 21.4 % rhinitis and 2.7 % eczema) and 116 children without atopy. The median age was 10.5 and 10.3 years for the atopic and non-atopic children, respectively. The prevalence of overweight or obese subjects was significantly greater in the atopic group (44.6 % vs 31.9 %, p < 0.05). The obese asthmatic children had a significantly higher prevalence of sleep disturbances due to wheezing in the last 12 months (45.5 % vs 15.9 %, p < 0.05). They also reported dry cough at night more often (50 % vs 28.6 %, p = 0.07), and a higher number of wheezing attacks in the past 12 months (72.7 % vs 50.8 %, p = 0.074), than the non-obese asthmatic children. Most of the obese atopic children were already overweight or obese at the time of the diagnosis (66.6 %). None of the associations were significantly different for boys or girls. Discussion: There is some evidence of an association between excess body weight or obesity and atopy - particularly asthma


Antecedentes: obesidad y atopia son dos importantes problemas de salud en aumento. El sobrepeso y la obesidad son potenciales factores de riesgo para la atopia, especialmente el asma. Objetivo y Métodos: determinar el índice de masa corporal (IMC) en niños con enfermedad atópica, comparándolo con niños no atópicos, y ver si la obesidad se asocia con una mayor gravedad de la enfermedad. Se seleccionaron niños de edad comprendida entre 5 y 16 años diagnosticados de enfermedad atópica, atendidos en el Ambulatorio del Centro Hospitalario. Como controles se seleccionaron niños entre 5 y 16 años, de una escuela de la misma área geográfica que los atópicos. Resultados: un total de 228 niños se incluyeron en el análisis: 112 niños atópicos (75,9% asma, 21,4% rinitis y 2,7% eccema), y 116 niños no atópicos. La edad media fue 10,5 y 10,3 años, respectivamente de ambos grupos. La prevalencia de sobrepeso o de obesidad fue significativamente mayor en el grupo de atópicos (44,6% vs 31,9%, p<0.05). La prevalencia de trastornos del sueño, por disnea, en los últimos 12 meses, había sido significativamente mayor en los asmáticos obesos (45.5% vs 15.9%, p<0.005). También tuvieron tos seca por la noche con mayor frecuiencia(50% vs 28.6%, p=0.07), y mayor número de crisis de asma en los últimos 12 meses (72.7% vs 50.8%, p=0.074), que los asmáticos no obesos. Muchos de los niños atópicos obesos eran ya obesos o tenían sobrepeso cuando fueron diagnosticados de su enfermedad (66,6%). En ninguno de estos hallazgos hubo diferencia entre varones o niñas. Discusión: hay alguna evidencia de asociación entre el exceso de peso corporal o la obesidad, con la atopia, especialmente asma


Subject(s)
Male , Female , Child , Adolescent , Humans , Hypersensitivity/complications , Obesity/complications , Body Mass Index , Risk Factors , Rhinitis/etiology , Immunotherapy , Asthma/etiology , Severity of Illness Index , Skin Tests
5.
Phys Rev Lett ; 84(18): 4056-9, 2000 May 01.
Article in English | MEDLINE | ID: mdl-10990609

ABSTRACT

The ground state of the proton-rich, unbound nucleus 11N was observed, together with six excited states using the multinucleon transfer reaction 10B(14N,13B)11N at 30A MeV incident energy at Grand Accelerateur National d'Ions Lourds. Levels of 11N are observed as well defined resonances in the spectrum of the 13B ejectiles. They are localized at 1.63(5), 2.16(5), 3.06(8), 3.61(5), 4.33(5), 5.98(10), and 6.54(10) MeV above the 10C+p threshold. The ground-state resonance has a mass excess of 24.618(50) MeV; the experimental width is smaller than theoretical predictions.

7.
Nature Biotechnol ; 15(8): p.807-8, 1997.
Article in English | Sec. Est. Saúde SP, SESSP-IBPROD, Sec. Est. Saúde SP | ID: but-ib13085
9.
12.
Rio de Janeiro; Guanabara Koogan; 1978. 238 p.
in Portuguese | DANTEPAZZANESE, SESSP-IDPCACERVO | ID: dan-730

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