ABSTRACT
Sulfadiazine is one of the drugs of choice in the treatment of paracoccidioidomycosis. Side effects are uncommon. Cutaneous and gastrointestinal reactions and rarely leucopenia and jaundice may occur. A patient on sulfadiazine 6 g daily exhibiting a good response is reported. On the 12th day, he presented an intense abdominal pain and reduced urinary output. An ultrasonography revealed diffuse calculosis in urinary tract. Peritoneal dialysis, urinary alkalinization and rehydration were instituted with complete restoration of renal function. This case illustrates the importance of an adequate hydratation of patients receiving sulfadiazine, a simple measure in the prevention of this uncommon complication which carries a high morbidity.
Subject(s)
Acute Kidney Injury/chemically induced , Lung Diseases, Fungal/drug therapy , Paracoccidioidomycosis/drug therapy , Sulfadiazine/adverse effects , Humans , Male , Middle Aged , Sulfadiazine/therapeutic useABSTRACT
A linfadenite e uma importante forma de acometimento tuberculoso extra-pulmonar que contribui com 8,4 por cento do total de casos de tuberculose nos adultos tratados em nosso Servico. A exerese ganglionar com exame histologico do fragmento, propiciou o diagnostico em 77,8 por cento dos casos. A boa evolucao clinica e a alta porcentagem de reatores ao PPD (84,2 por cento) faz-nos supor a predominancia de M. tuberculosis como o agente etiologico da linfadenite na nossa serie. Houve boa resposta em 75 por cento dos pacientes submetidos ao esquema quimioterapico com seis meses de duracao.
Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Tuberculosis, Lymph Node/diagnosis , Biopsy , Brazil/epidemiology , Lymph Nodes/pathology , Prevalence , Retrospective Studies , Tuberculosis, Lymph Node/epidemiologyABSTRACT
Descrevemos quatro casos de estenose bronquica, uma complicacao rara de tuberculose pulmonar. No primeiro caso, uma mulher de 18 anos, sem tratamento previo para tuberculose, apresentou estenose bronquica como resultado da cicatrizacao de complexo primario. Nao havia lesao de parenquima ao raio X. Nos outros tres pacientes a estenose bronquica foi atribuida a tuberculose ativa com pesquisa positiva para bacilo alcool-acido resistente em escarro. Estes receberam tratamento para tuberculose. Em um deles isto foi suficiente para a resolucao da estenose, mas nos outros dois pacientes ocorreu estenose bronquica devido a fibrose.
Subject(s)
Humans , Female , Adult , Aged , Bronchial Diseases/etiology , Tuberculosis, Pulmonary/complications , Bronchial Diseases , Bronchial Diseases/drug therapy , Bronchial Diseases/pathology , Bronchography , Constriction, Pathologic , Constriction, Pathologic/drug therapy , Constriction, Pathologic/etiology , Constriction, Pathologic/pathology , Tuberculosis, Pulmonary , Tuberculosis, Pulmonary/drug therapy , Tuberculosis, Pulmonary/pathologyABSTRACT
Tuberculous lymphadenitis is a form of extrapulmonary tuberculosis that was observed in 8.4% of all cases with tuberculosis in our series. In all instances the organism isolated was M. tuberculosis. There was a high rate of PPD positiveness. The chemotherapy yielded good results. The evolution was satisfactory in 75% of the patients treated for six months.
Subject(s)
Tuberculosis, Lymph Node/diagnosis , Adolescent , Adult , Aged , Biopsy , Brazil/epidemiology , Female , Humans , Lymph Nodes , Male , Middle Aged , Prevalence , Retrospective Studies , Tuberculosis, Lymph Node/epidemiologyABSTRACT
Four cases of bronchial stenosis as an unusual complication of tuberculosis are described. In the first case, a 18-year-old woman, the bronchial stenosis resulted from cicatrization of a primary focus. The X-ray examination showed no pulmonary lesion and she did not receive any specific treatment for tuberculosis. In other three patients the bronchial stenosis was due to active disease, and there were acid-fast bacilli in the sputum. They received treatment for tuberculosis which resulted in resolution of stenosis in one of them while in the other two the fibrotic bronchial stenosis persisted.
