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1.
J Clin Rheumatol ; 14(4): 226-9, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18766123

ABSTRACT

We describe a case of simultaneous severe lupus enteritis and lupus cystitis in a 38-year-old female with a 21-year history of systemic lupus erythematosus (SLE). The patient presented with acute abdominal pain, decreased urinary output, associated low-grade fever, nausea, and diarrhea. She had serologic evidence of an SLE flare with acute renal insufficiency. Computed tomography examination revealed dramatic edema of the large- and small-bowel walls with no evidence of bowel loop dilatation or pneumatosis intestinalis, marked diffuse thickening of the urinary bladder wall, and bilateral hydronephrosis and hydroureter. Lupus enteritis and lupus cystitis were diagnosed and treatment with intravenous corticosteroids led to prompt resolution of the abdominal pain and normalization of renal function. Because infarction of tissue and bowel rupture are potentially fatal complications, it is essential to consider lupus enteritis in SLE patients who present with abdominal pain. This case demonstrates that once lupus enteritis is suspected, coexistent lupus cystitis must also be considered.


Subject(s)
Cystitis/complications , HIV Infections/complications , Lupus Erythematosus, Systemic/complications , Abdominal Pain/etiology , Acute Kidney Injury/etiology , Adrenal Cortex Hormones/administration & dosage , Adult , Antiviral Agents/therapeutic use , Cystitis/drug therapy , Cystitis/pathology , Female , Ganciclovir/therapeutic use , HIV Infections/drug therapy , Humans , Infusions, Intravenous , Lupus Erythematosus, Systemic/drug therapy
2.
Reprod Sci ; 14(5): 440-4, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17913963

ABSTRACT

The objective of this study is to describe magnetic resonance (MR) signal intensity (SI) changes in the cervix during pregnancy. This is an observational cohort study of women with a history of preterm delivery. MR imaging sequences were performed every 3 to 4 weeks. Using 8 regions of interest, the SIs are quantified and analyzed with respect to gestational age. Twenty-seven MR studies were performed on a cohort of 8 women. The SIs of the external os are significantly greater than those of the internal os ( P = .035). Similarly, the SIs of the outer stroma are greater than those of the inner stroma (P = .002). As gestational age advances, the inner to outer stromal SI ratio increases, primarily because of a decreasing SI in the outer stromal layer (P = .03). The MR SIs of the cervical stromal zones display variability during pregnancy and decrease with advancing gestation.


Subject(s)
Cervix Uteri/cytology , Magnetic Resonance Imaging/methods , Pregnancy , Adult , Cervix Uteri/physiology , Cohort Studies , Female , Humans , Pregnancy/physiology , Pregnancy Trimester, Second/physiology , Pregnancy Trimester, Third/physiology , Premature Birth/prevention & control , Prenatal Care/methods , Stromal Cells/cytology , Stromal Cells/physiology , Time Factors
3.
J Thorac Imaging ; 21(3): 197-204, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16915064

ABSTRACT

We have analyzed the radiographic and computed tomographic (CT) appearance of thoracostomy (chest) tubes inadvertently placed into the lungs. We have studied the clinical sequela of such malpositioning and discussed treatment options. Cases were collected from chest CT log book reports between January 1998 and January 31, 2005 which indicated or suggested intrapulmonary thoracostomy tube placement. CT scans were reviewed by the authors. The chest radiographs and medical records--including thoracic surgical reports--of those patients whose scans demonstrated intrapulmonary tube placement or indeterminate tube location were reviewed. Fifty patients, in whom 51 thoracostomy tubes were placed into the lungs, are included in this series. None of these tubes were described as intrapulmonary on reports of chest radiographs done before CT scanning. In 13 patients (26%), thoracostomy tube placements produced immediate improvement in pleural abnormalities. Dramatic increase or development of chest wall emphysema or pneumothorax was noted in 4 (8%) patients after tube placement. Twenty-five patients (50%) demonstrated either abrupt or gradual increase in pulmonary or pleural opacity on postplacement chest radiographs. Twenty-one (42%) had no apparent clinical complications. Thirteen (26%) had either prolonged air leaks or recurrent pneumothorax. Ten (20%) developed pneumonia. Retained hemothorax or empyema occurred in 8 (16%). Twelve patients (24%) required subsequent thoracic surgery. Intrapulmonary placement of thoracostomy tubes is probably more common than previously reported. This possibility should be considered when radiographs and CT scans are evaluated.


Subject(s)
Chest Tubes/adverse effects , Lung Injury , Lung/diagnostic imaging , Pneumonia/etiology , Pneumothorax/etiology , Thoracostomy/adverse effects , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Iatrogenic Disease , Male , Medical Errors , Middle Aged , Pneumonia/diagnostic imaging , Pneumothorax/diagnostic imaging , Radiography, Thoracic , Retrospective Studies , Tomography, X-Ray Computed
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