Unilateral graft rejection after bilateral antigenically identical corneal transplantation.

A unique case of unilateral graft rejection after bilateral antigenically identical corneal transplantation is described. The local risk factors (corneal vascularity and elevated intraocular pressure) were present to a greater extent in the nonrejected eye. The influence of other factors on the corneal microenvironment and their relationship to graft/host interactions is discussed.