ABSTRACT
The X-ray structure analysis of [Ni(C(5)H(8)N(2))(4)(H(2)O)(2)]Cl(2) was undertaken to elucidate the geometry around the Ni(2+) ion. The molecule lies on a twofold axis which runs through the O-Ni-O atoms. The geometry around the Ni(2+) ion is best described as slightly distorted tetragonal bipyramidal.
Subject(s)
Nickel/chemistry , Organometallic Compounds/chemistry , Pyrazoles/chemistry , Crystallography, X-Ray , Molecular StructureABSTRACT
The saturated part of the isoquinoline moiety in the title compound, C17H19NO2, has a twist conformation and the phenyl ring substituent is in an equatorial position. The absolute configuration of the molecule is R and molecules form infinite chains by means of weak hydrogen bonds.
Subject(s)
Adrenergic beta-Antagonists/chemistry , Isoquinolines/chemistry , Tetrahydroisoquinolines , Crystallography, X-Ray , Hydrogen Bonding , Molecular Conformation , Molecular StructureABSTRACT
The synthesis and biological activity of new 10-13 membered oxygen-nitrogen heterocyclic systems condensed with two aromatic rings is reported. The structure-activity relationship of these new compounds in X-ray investigation has been studied. Pharmacological investigations have shown that the compounds exhibit weak neuroleptic activity.
