ABSTRACT
Two Drosophila melanogaster strains (Canton-S and ri-lines) for 20 generations were in the controlled terms of chronic irradiation with 3-dose rate (1,2 x 10(-8); 0,3 x 10(-8); 0,12 x 10(-8) Gy/c). The dynamics of hybrid dysgenesis frequency was explored for each generation of F1 descendants from Canton-S and ri-lines crossing. The gradual change of dose response of hybrid dispense depending on duration of irradiation of ancestors and dose rate was shown. The complex dynamics of hybrid dysgenesis frequency depending on irradiation duration of ancestors and dose rate was detected. The cumulative effect of the prolonged irradiation shows up as adaptation at the lowest dose rate and as exhaustion at the highest dose rate. Question comes into discussion about the features of transitional process and including of protective and adaptive reactions hierarchy at the conditions of radiation factor chronic action.
Subject(s)
Abnormalities, Radiation-Induced/etiology , Drosophila melanogaster/radiation effects , Gamma Rays/adverse effects , Gonadal Dysgenesis/etiology , Abnormalities, Radiation-Induced/genetics , Adaptation, Physiological/genetics , Adaptation, Physiological/radiation effects , Animals , Crosses, Genetic , DNA Transposable Elements/genetics , Dose-Response Relationship, Radiation , Drosophila melanogaster/genetics , Drosophila melanogaster/growth & development , Female , Gonadal Dysgenesis/genetics , MaleABSTRACT
Verification of hypothesis about mobile element activation radiosensitivity change in the conditions of the prolonged irradiation was the research goal. The estimation of orientation of these changes depending on the accumulated dose and their characteristic times were conducted. Two Drosophila melanogaster strains (Canton-S and P-lines) for 20 generations were in the controlled terms of chronic irradiation with 3-dose rate (1.2 x 10(-8), 0.6 x 10(-8) and 0.12 x 10(-8) Gy/c). The dynamics of hybrid dysgenese frequency was explored for each generation of F1 descendants from Canton-S and P-lines crossing. The gradual change of dose response of hybrid disgenesis depending on duration of irradiation of ancestors and dose rate was shown. The complex dynamics of hybrid dysgenese frequency depending on irradiation duration of ancestors and dose rate was shown. The cumulative effect of the prolonged irradiation shows up as adaptation at the lowest dose rate and as exhaustion at the highest dose rate. Question comes into discussion about the features of transitional process and including of protective and adaptive reactions hierarchy at the conditions of radiation factor chronic action.
