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1.
Pediatr Diabetes ; 18(4): 315-319, 2017 06.
Article in English | MEDLINE | ID: mdl-27161659

ABSTRACT

BACKGROUND/OBJECTIVE: The impact of family composition on glycemic control in children with type 1 diabetes remains unclear. We sought to evaluate the relationship between health insurance coverage, family composition, and insulin management, and assess their impact on glycemic control in a pediatric type 1 diabetes population. METHODS: A retrospective chart review was completed for patients seen in the Pediatric Endocrinology Clinic at the University of Louisville in 2012. RESULTS: The analysis included 729 patients with type 1 diabetes; 268 (37%) had public insurance while 461(63%) had private insurance. Compared with publicly insured patients, privately insured patients had higher rates of intensive insulin management with multiple daily injections (MDI) plans or pump devices (88 vs. 83.2%, p = 0.066) and lower HbA1c levels [8.57 vs. 9.39% (70 vs. 79 mmol/mol), p < 0.001]. Of the 729 patients, 243 were in single-adult homes (33%). Single-adult homes had higher HbA1c levels than two-adult homes, [9.3 vs. 8.6% (78 vs. 70 mmol/mol), p < 0.001]. Among publicly insured, there was no difference in HbA1c levels for single-adult vs. two-adult homes [9.4 (79 mmol/mol), p = 0.868]. For privately insured, patients in single-adult homes had higher HbA1c levels than peers in two-adult homes [9.2 vs. 8.4% (77 vs. 68), p < 0.001]. CONCLUSION: Insurance type and family composition have significant associative effects on glycemic control and insulin management that may be mitigated by insulin pump therapy. Identifying and addressing factors such as availability of resources, family education, and adult support and supervision, may help improve glycemic control in high-risk pediatric diabetes patients.


Subject(s)
Diabetes Mellitus, Type 1/drug therapy , Family , Hyperglycemia/prevention & control , Hypoglycemic Agents/administration & dosage , Insulin/administration & dosage , Insurance, Health , Self-Management , Biomarkers/blood , Cohort Studies , Combined Modality Therapy/economics , Diabetes Mellitus, Type 1/blood , Diabetes Mellitus, Type 1/economics , Diabetes Mellitus, Type 1/therapy , Drug Administration Schedule , Female , Glycated Hemoglobin/analysis , Health Expenditures , Hospitals, University , Humans , Hyperglycemia/economics , Hypoglycemic Agents/economics , Hypoglycemic Agents/therapeutic use , Insulin/economics , Insulin/therapeutic use , Insulin Infusion Systems/economics , Kentucky , Male , Outpatient Clinics, Hospital , Retrospective Studies , Self-Management/economics , Single Parent
2.
J Pediatr Endocrinol Metab ; 28(5-6): 721-4, 2015 May.
Article in English | MEDLINE | ID: mdl-25581742

ABSTRACT

We report a 9-year-old female who presented with new onset intractable seizure activity followed by a prolonged encephalopathic state. After ruling out common etiologies, Hashimoto's encephalopathy (HE) was considered, and antibody levels to thyroid peroxidase and thyroglobulin were both markedly elevated in her serum. She was euthyroid at the time of presentation. Upon treatment with high dose methylprednisolone, the patient demonstrated a significant improvement in her encephalopathy. The diagnosis of HE requires strong clinical suspicion with evidence of antithyroid antibodies, as well as an encephalopathy not explained by another etiology. While well documented in the adult literature, only a handful of pediatric cases have been described to date. Patients with HE have a nearly universal response to high dose glucocorticoids. HE should be considered in the differential diagnosis of any patient, adult or pediatric, who displays prolonged, unexplainable encephalopathy.


Subject(s)
Encephalitis/diagnosis , Hashimoto Disease/diagnosis , Child , Encephalitis/complications , Encephalitis/drug therapy , Female , Hashimoto Disease/complications , Hashimoto Disease/drug therapy , Humans , Magnetic Resonance Imaging , Methylprednisolone/therapeutic use , Seizures/complications
3.
Diabetes Res Clin Pract ; 90(1): 40-4, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20630611

ABSTRACT

AIMS: To examine the association between health insurance coverage, insulin management plans, and their impact on diabetes control in a pediatric type 1 diabetes mellitus clinic population. METHODS: Retrospective cohort design drawn from the medical records of the Pediatric Endocrinology Clinic at the University of Louisville, Kentucky. RESULTS: Out of 701 patients, 223 had public insurance, and 478 had private insurance. 77% of publically insured used two or three injections per day vs. 40% private. Conversely, 58% of privately insured used a multiple daily injection (MDI) plan or insulin pump (vs. 21%). 84% of MDI patients had private insurance with 93% using insulin pens compared with 38% of publically insured. Mean HbA1c was 8.6% for privately insured vs. 9.8% public, p<0.0001. Privately insured MDI and pump patients had the lowest HbA1cs. CONCLUSIONS: Insurance type had a significant effect on the insulin management plan used and was the most significant factor in overall diabetes control. Limitations on insulin pen use and number of glucose test strips may play a role in the decreased use of MDI/insulin pumps by publicly insured patients. Addressing factors related to insurance type, including availability of resources, could substantially improve diabetes control in those with public insurance.


Subject(s)
Diabetes Mellitus, Type 1/drug therapy , Diabetes Mellitus, Type 1/economics , Hypoglycemic Agents/therapeutic use , Insulin/therapeutic use , Insurance Coverage/statistics & numerical data , Insurance, Health , Adolescent , Blood Glucose Self-Monitoring/economics , Child , Child, Preschool , Cohort Studies , Diabetes Mellitus, Type 1/blood , Female , Glycated Hemoglobin/analysis , Hospitals, University , Humans , Hypoglycemic Agents/administration & dosage , Hypoglycemic Agents/economics , Insulin/administration & dosage , Insulin/economics , Insulin Infusion Systems/statistics & numerical data , Male , Medical Records , National Health Insurance, United States , Outpatient Clinics, Hospital/statistics & numerical data , Retrospective Studies , United States , Young Adult
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