Placement of double-J stent in patients with malignant ureteral obstruction: antegrade or retrograde approach?

AIM: To determine whether antegrade or retrograde methods should be preferred for double-J stent placement in patients with malignant ureteral obstruction (MUO). MATERIAL AND METHODS: The medical records of patients treated for MUO in the Urology and Interventional Radiology Clinic, Konya Training and Research Hospital, were reviewed retrospectively. Patients with benign aetiology were excluded from the study. Reports of the procedures, ultrasonography findings, computed tomography (CT), angiography, and pyelography images and the follow-up records of patients with MUO were assessed. A total of 111 patients and 114 ureteral stenting treatments were included in the study; 63 (55.3%) were operated on using the antegrade ureteral stenting (AUS) method, whereas 51 (44.7%) were operated on using the retrograde ureteral stenting (RUS), method, and the characteristics of these groups were evaluated. The presence of hydroureteronephrosis and ureteral tortuosity were determined. RESULTS: Overall success rates were found to be 95.2% using the AUS method and 47.1% using the RUS method. The technical success of the antegrade method was significantly higher in patients with or without tortuosity (respectively: p=0.005, Z shape p=0.001, pigtail shape p=0.035″). The technical success of the antegrade method was significantly higher in patients with hydroureteronephrosis (p=0.001). CONCLUSION: The AUS technique should be the first choice for double-J stent placement in patients with MUO.

Childhood trauma and dissociation in patients with obsessive compulsive disorder.

BACKGROUND AND OBJECTIVE: The present study attempted to assess childhood trauma events and dissociative symptoms in patients with obsessive compulsive disorder (OCD). METHOD: The study included all patients who were admitted for the first time to the psychiatric outpatient unit over a 24-month period. Seventy-eight patients were diagnosed as having OCD during the two-year study period. Childhood traumatic events were assessed with a Childhood Trauma Questionnaire (CTQ). Obsessive compulsive disorder symptoms were assessed with the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). A Dissociation Questionnaire (DIS-Q) was also used to measure dissociative symptoms. RESULTS: The mean of Y-BOCS points were 23.37 +/- 7.27. Dissociation questionnaire scores were between 0.40 and 3.87 and the mean was 2.23 +/- 0.76. Childhood trauma points were 1.27-4.77 and the mean was 2.38 +/- 0.56. There was no statistically significant relationship between Y-BOCS points and childhood trauma points (p > 0.05). There was a statistically significant positive relationship between Y-BOCS points and DIS-Q points. There was no statistically significant relationship between DIS-Q points and childhood trauma points (p > 0.05). CONCLUSION: Childhood trauma questionnaire points might be significant clinically, although there was not a statistically significant correlation in our study. We also conclude that dissociative symptoms among patients with OCD should alert clinicians to treatment of the disorder.

An extremely rare case: osteosclerotic metaphyseal dysplasia.

OMD (osteosclerotic metaphyseal dysplasia) is a very rare sclerosing bone disorder, first described by G. Nishimura in two Japanese siblings in 1993 (6). We report the case of a 12-month-old male with hypotonia, developmental delay and sclerosis of the metaphyses and epiphyses of specific bones. This 36-week gestation boy was born to a 26 year old gravida 5 para 1 Turkish mother and a 27 year old nonconsanguineous father. Radiographic findings obtained during the hospital stay included bilateral symmetrical osteosclerosis of the metaphyseal portions of the long bones in the upper and lower extremities with osteopenic shafts. Narrow bands of metaphyseal osteosclerosis were detected in the short tubular bones of the hands and feet. Growing parts of bilateral scapula, iliac, pubic and ischial bones show sclerotic bands. In addition superior and inferior plates of vertebras, transverse processes of sacral vertebras, all visible epiphyses, carpal and tarsal bones also show sclerotic changes. The scalp was unaffected. Based on the clinical, radiographic, and laboratory findings, a diagnosis of OMD was made. We do not know any of the osteosclerotic bone disorder with changes including hypotonia, mental and motor developmental delay and metaphyseal sclerosis of the bones with a unique distribution except OMD. The syndrome is characterized by developmental delay of a progressive nature, hypotonia, elevated alkaline phosphatase, and late-onset spastic paraplegia 18 years ago. Our patient is the 4th case of OMD described in the literature share some clinical and radiological similarities with other three reported cases of osteosclerotic metaphyseal dysplasias.

Childhood trauma and dissociation in patients with obsessive compulsive disorder / Traumas de infancia y disociación en pacientes con trastornos obsesivo-compulsivos

BACKGROUND AND OBJECTIVE: The present study attempted to assess childhood trauma events and dissociative symptoms in patients with obsessive compulsive disorder (OCD). METHOD: The study included all patients who were admitted for the first time to the psychiatric outpa- tient unit over a 24-month period. Seventy-eight patients were diagnosed as having OCD during the two-year study period. Childhood traumatic events were assessed with a Childhood Trauma Questionnaire (CTQ). Obsessive compulsive disorder symptoms were assessed with the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). A Dissociation Questionnaire (DIS-Q) was also used to measure dissociative symptoms. RESULTS: The mean of Y-BOCS points were 23.37 ± 7.27. Dissociation questionnaire scores were between 0.40 and 3.87 and the mean was 2.23 ± 0.76. Childhood trauma points were 1.27-4.77 and the mean was 2.38 ± 0.56. There was no statistically significant relationship between Y-BOCS points and childhood trauma points (p > 0.05). There was a statistically significant positive relationship between Y-BOCS points and DIS-Q points. There was no statistically significant relationship between DIS-Q points and childhood trauma points (p > 0.05) CONCLUSION: Childhood trauma questionnaire points might be significant clinically, although there was not a statistically significant correlation in our study. We also conclude that dissociative symptoms among patients with OCD should alert clinicians to treatment of the disorder.

ANTECEDENTES Y OBJETIVO: El presente estudio tuvo por objeto evaluar eventos traumáticos de la infancia, y síntomas disociativos en pacientes con trastorno obsesivo-compulsivo (TOC). MÉTODO: El estudio incluyó a todos los pacientes que fueron ingresados por primera vez en la Unidad Psiquiátrica, a lo largo de un período de 24 meses. A setenta y ocho pacientes les fue diagnosticado TOC durante un período de dos años. Los eventos traumáticos de la infancia fueron evaluados mediante un Cuestionario de traumas de infancia (CTQ). Los síntomas del trastorno obsesivo-compulsivo fueron evaluados mediante la Escala Yale-Brown para el trastorno obsesivo-compulsivo (Y-BOCS). Asimismo, para medir los síntomas disociativos, se usó un Cuestionario de disociación (DIS-Q). RESULTADOS: Los puntos promedios del cuestionario Y-BOCS fueron 23.37 ± 7.27. Las puntuaciones del Cuestionario de disociación estuvieron entre 0.40 y 3.87 y la media fue 2.23 ± 0.76. Los puntos por trauma de infancia fueron 1.27-4.77 y la media fue 2.38 ± 0.56. No hubo relación estadísticamente significativa entre los puntos de Y-BOCS, y los puntos por trauma de la infancia (p > 0.05). Hubo una relación positiva estadísticamente significativa entre los puntos de Y-BOCS y los puntos de DIS-Q. No hubo una relación estadísticamente significativa entre los puntos de DIS-Q y los puntos por trauma de la infancia (p > 0.05). CONCLUSIÓN: Los puntos del Cuestionario de traumas de infancia podrían ser clínicamente significativos, aunque no hubo una correlación estadísticamente significativa en nuestro estudio. También concluimos que los síntomas disociativos entre los pacientes con TOC deben alertar a los clínicos médicos al tratamiento de este trastorno.

Assesment of psychiatric symptoms and co-morbidities in patients with irritable bowel syndrome / Evaluación de los síntomas psiquiátricos y las comorbilidades en pacientes con el síndrome del intestino isrritable

AIM: To determine the psychiatric symptom assesment of patients seeking treatment for irritable bowel syndrome (IBS) and to demonstrate the presence of more complicated psychiatric disorders. SUBJECTS AND METHOD: The participants were recruited from patients who were attending internal medicine and gastroenterology clinics and who fullfilled the Rome III criteria for IBS. Fifty patients with IBS (IBS group) and 50 patients with complaints other than gastrointestinal symptoms (control group) were randomly selected. All participants were screened by the Structured Clinical Interview for DSM-IV (SCID-I), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Symptom Check list - 90 (Revised) [SCL-90-R]. RESULTS: Seventeen patients (34%) and three control subjects (6%) had at least one psychiatric diagnosis (p = 0.001). Global severity index (GSI) total scores and SCL-90-R items were significantly higher in the IBS group than the control group (0.92 ± 0.46 vs 0.358 ± 0.19, p < 0.001). Beck anxiety inventory and BDI scores were higher in the IBS group than the control group (p < 0.001). Axis-I psychiatric disorders diagnosed with SCID-I were significantly higher in the IBS group (34% vs 6%) [p = 0.001]. Among the Axis-I disorders, somatoform and anxiety disorders were higher in the patient group than in the control subjects (p = 0.002 and p = 0.0057) whereas there was no difference for mood disorders (p = 0.204). Seven (14%) of the patients and two (4%) of the control subjects had at least one Axis-II psychiatric disorder diagnosed with SCID-II without any significance (p = 0.159). CONCLUSION: These findings suggest that except for mood and personality disorders, almost all psychiatric symptoms and disease co-morbities with IBS are higher than in the sample without IBS. We can easily use SCL-90-R, BAI and BDI in internal medicine and gastroenterology clinics to detect psychiatric symptom levels and then to refer patients to a psychiatrist for further evaluation and treatment.

OBJETIVO: Determinar la evaluación del síntoma psiquiátrico de pacientes que buscan tratamiento para el síndrome del intestino irritable (IBS), y demostrar la presencia de trastornos psiquiátricos más complicados. SUJETOS Y MÉTODO: Los participantes reclutados fueron pacientes que asistían a clínicas de medicina interna y gastroenterología, y satisfacían los criterios de Roma III para el IBS Cincuenta pacientes con IBS (grupo IBS) y 50 pacientes aquejados de otras dolencias no gastrointestinales (grupo control) fueron seleccionados al azar. Todos los participantes pasaron por el tamiz de la Entrevista Clínica Estructurada para DSM-IV (SCID-I), el Inventario de Depresión de Beck (BDI), el Inventario de Ansiedad de Beck (BAI), y el Listado de Síntomas-90 (Revisado) [SCL-90-R]. RESULTADOS: Diecisiete pacientes (34%) y tres sujetos de control (6%) tenían al menos un diagnóstico psiquiátrico (p = 0.001). Las puntuaciones totales del índice de severidad global (GSI) y los ítems del SCL-90-R fueron significativamente más altos en el grupo de IBS que en el grupo control (0.92 ± 0.46 frente a 0.358 ± 0.19, p < 0.001). Las puntuaciones del Inventario de Ansiedad de Beck y BDI fueron más altas en el grupo IBS que el grupo control (p < 0.001). Los trastornos psiquiátricos del eje I diagnosticados con SCID-I fueron significativamente más altos en el grupo IBS (34% vs. 6%) [p = 0.001]. Entre los desórdenes del Eje I, los trastornos somatoformos y los trastornos de ansiedad fueron más altos en el grupo de pacientes que en los sujetos del control (p = 0.002) y (p = 0.0057), en tanto que no hubo ninguna diferencia en cuanto a los trastornos de estados de ánimo (p = 0.204). Siete (14%) de los pacientes y dos (4%) de los sujetos del control tuvieron por lo menos un trastorno psiquiátrico del eje II diagnosticados con el SCID-II sin ninguna significación (p = 0.159). CONCLUSIÓN: Estos hallazgos sugieren que salvo el caso de los trastornos de estados de ánimo y personalidad, casi todos los síntomas psiquiátricos y comorbilidades con el IBS son más altos que en la muestra sin IBS. Se puede usar con facilidad el SCL-90-R, el BAI y el BDI en las clínicas de medicina interna y gastroenterología para detectar los niveles de síntomas psiquiátricos, y remitir entonces a los pacientes a un psiquiatra para ulterior evaluación y tratamiento.

Assesment of psychiatric symptoms and co-morbidities in patients with irritable bowel syndrome.

AIM: To determine the psychiatric symptom assessment of patients seeking treatment for irritable bowel syndrome (IBS) and to demonstrate the presence of more complicated psychiatric disorders. SUBJECTS AND METHOD: The participants were recruited from patients who were attending internal medicine and gastroenterology clinics and who fullfilled the Rome III criteria for IBS. Fifty patients with IBS (IBS group) and 50 patients with complaints other than gastrointestinal symptoms (control group) were randomly selected. All participants were screened by the Structured Clinical Interview for DSM-IV (SCID-I), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Symptom Check list - 90 (Revised) [SCL-90-R]. RESULTS: Seventeen patients (34%) and three control subjects (6%) had at least one psychiatric diagnosis (p = 0.001). Global severity index (GSI) total scores and SCL-90-R items were significantly higher in the IBS group than the control group (0.92 +/- 0.46 vs 0.358 +/- 0.19, p < 0.001). Beck anxiety inventory and BDI scores were higher in the IBS group than the control group (p < 0.001). Axis-I psychiatric disorders diagnosed with SCID-I were significantly higher in the IBS group (34% vs 6%) [p = 0.001]. Among the Axis-I disorders, somatoform and anxiety disorders were higher in the patient group than in the control subjects (p = 0.002 and p = 0.0057) whereas there was no difference for mood disorders (p = 0.204). Seven (14%) of the patients and two (4%) of the control subjects had at least one Axis-II psychiatric disorder diagnosed with SCID-II without any significance (p = 0.159). CONCLUSION: These findings suggest that except for mood and personality disorders, almost all psychiatric symptoms and disease co-morbities with IBS are higher than in the sample without IBS. We can easily use SCL-90-R, BAI and BDI in internal medicine and gastroenterology clinics to detect psychiatric symptom levels and then to refer patients to a psychiatrist for further evaluation and treatment.