ABSTRACT
Orbital lipoma is a rare entity with only a small number of cases previously described. The authors describe a case of orbital lipoma in a 56-year-old man, which was treated with surgical excision. Cytogenetic analysis of the lesion demonstrated abnormalities of chromosome 12, consistent with chromosomal abnormalities in lipomas found elsewhere in the body. Therefore, cytogenetic analysis may be useful to differentiate lipomatous tumors from normal orbital fat.
Subject(s)
Chromosome Aberrations , Chromosomes, Human, Pair 12 , Lipoma/genetics , Orbital Neoplasms/genetics , Cytogenetic Analysis , Humans , In Situ Hybridization, Fluorescence , Lipoma/diagnosis , Lipoma/surgery , Magnetic Resonance Imaging , Male , Middle Aged , Orbital Neoplasms/diagnosis , Orbital Neoplasms/surgery , Tomography, X-Ray ComputedABSTRACT
Mohs' micrographic surgery (MMS) is an effective means of margin control in the management of periocular basal cell carcinomas (BCC). We describe three cases of recurrent BCC that presented with progressive eyelid contracture after MMS. They illustrate high-risk factors for recurrence, namely large tumor size, medial canthal location, previous treatment, and aggressive histological features. Careful long-term surveillance with serial photography may identify early eyelid contracture and thus assist in the detection of recurrent BCC after MMS and improve patient outcome.
Subject(s)
Carcinoma, Basal Cell/surgery , Contracture/pathology , Eyelid Neoplasms/surgery , Mohs Surgery , Aged , Aged, 80 and over , Carcinoma, Basal Cell/pathology , Contracture/etiology , Disease Progression , Eyelid Neoplasms/pathology , Female , Humans , Male , Middle Aged , Neoplasm Recurrence, Local/pathologyABSTRACT
Cholesterol granuloma is an uncommon entity, occurring typically in the supero-temporal orbit. Recurrence has only rarely been reported. We describe a case of recurrent cholesterol granuloma in a 48-year-old-man to illustrate the clinical features of the condition, and to highlight the importance of complete resection to prevent recurrence.
