Subject(s)
Cranial Nerve Diseases/diagnosis , Eye Infections, Viral/diagnosis , Herpes Zoster Ophthalmicus/diagnosis , Ocular Motility Disorders/diagnosis , Orbital Diseases/diagnosis , Abducens Nerve Diseases/diagnosis , Abducens Nerve Diseases/drug therapy , Abducens Nerve Diseases/virology , Acyclovir/therapeutic use , Aged , Antiviral Agents/therapeutic use , Cranial Nerve Diseases/drug therapy , Cranial Nerve Diseases/virology , Epithelium, Corneal/pathology , Eye Infections, Viral/drug therapy , Eye Infections, Viral/virology , Female , Glucocorticoids/therapeutic use , Herpes Zoster Ophthalmicus/drug therapy , Herpes Zoster Ophthalmicus/virology , Humans , Male , Ocular Motility Disorders/drug therapy , Ocular Motility Disorders/virology , Oculomotor Nerve Diseases/diagnosis , Oculomotor Nerve Diseases/drug therapy , Oculomotor Nerve Diseases/virology , Optic Nerve Diseases/diagnosis , Optic Nerve Diseases/drug therapy , Optic Nerve Diseases/virology , Orbital Diseases/drug therapy , Orbital Diseases/virology , Prednisolone/therapeutic use , Trigeminal Nerve Diseases/diagnosis , Trigeminal Nerve Diseases/drug therapy , Trigeminal Nerve Diseases/virology , Trochlear Nerve Diseases/diagnosis , Trochlear Nerve Diseases/drug therapy , Trochlear Nerve Diseases/virologyABSTRACT
PURPOSE: To evaluate ocular biometric parameters and darkroom prone provocative test (DPPT) in family members of primary angle closure (PAC) glaucoma (PACG) patients and to establish any correlation between these biometric parameters and the DPPT response. METHODS: Seventy-four family members of PACG patients underwent ultrasound ocular biometry, slit lamp biomicroscopy, Goldmann applanation tonometry, fundus examination, and gonioscopy. Lastly, DPPT was performed. RESULTS: Of 74 family members examined, 6 (8.1%) were found to have PAC, 8 (10.8%) were PAC suspects, and 60 (81.1%) were unaffected. Of those affected, 4 (66.7%) had a positive DPPT response, whereas 87.5% of the PAC suspects had a positive or a borderline DPPT response. Affected and PAC suspects had the shallowest anterior chamber depth, thickest lens, shortest axial length, and most anteriorly positioned lens. Anterior chamber depth and lens thickness showed a significant correlation with positive DPPT. CONCLUSIONS: Anterior chamber depth and lens thickness and, to a lesser extent, axial length and lens position were significantly correlated with a positive DPPT response. The ocular biometric risk factors associated with PACG patients are also found in their respective family members who are affected and suspected of having PAC. We suggest a longitudinal study to determine the reliability of DPPT in identifying individuals who are at risk of PAC.
