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1.
Fam Cancer ; 17(2): 229-234, 2018 04.
Article in English | MEDLINE | ID: mdl-28887722

ABSTRACT

Familial adenomatous polyposis patients often present with non-malignant extra-intestinal manifestations which include dental anomalies that may be evident prior to the appearance of the colonic adenomas. The aims of this study were to describe the prevalence and type of dental anomalies and the relationships between gene mutations and dental anomalies in these patients. Twenty-two pediatric familial adenomatous polyposis patients and 46 controls, who were age and gender matched participated. Familial adenomatous polyposis patient's had a dental examination with panoramic radiograph and medical record review for age at diagnosis, the presence of the adenomatous polyposis coli gene mutation, and determination of other extra-intestinal manifestations on the body. The control group was identified from a retrospective chart review and selected if there was a current panoramic radiograph. The only significant difference between familial adenomatous polyposis patients and controls were the presence of jaw osteomas and sclerosis (p = .0001). Patients with a mutation in, or upstream of codon 1309 had a higher frequency of osteomas (77.8%) and jaw-bone sclerosis (44.4%), and 77% of these had at least one dental anomaly. This preliminary study showed an association between a genetic variant at, or upstream of codon 1309, and radiographic dental anomalies.


Subject(s)
Adenomatous Polyposis Coli Protein/genetics , Adenomatous Polyposis Coli/genetics , Dentofacial Deformities/epidemiology , Mandibular Neoplasms/epidemiology , Osteoma/epidemiology , Osteosclerosis/epidemiology , Adolescent , Case-Control Studies , Child , Dentofacial Deformities/diagnostic imaging , Dentofacial Deformities/genetics , Female , Humans , Jaw/diagnostic imaging , Jaw/pathology , Male , Mandibular Neoplasms/diagnostic imaging , Mandibular Neoplasms/genetics , Mutation , Osteoma/diagnostic imaging , Osteoma/genetics , Osteosclerosis/diagnostic imaging , Osteosclerosis/genetics , Prevalence , Radiography, Panoramic , Retrospective Studies
2.
BMC Oral Health ; 17(1): 116, 2017 Aug 10.
Article in English | MEDLINE | ID: mdl-28797247

ABSTRACT

BACKGROUND: Gastroesophageal reflux disease (GERD) affects 15-25% of children and adolescents in the United States. The diagnosis of GERD in children is complex as reported symptoms or symptom profiles have been found to be unreliable. Frequently, the diagnosis must be confirmed by objective tests such as pH monitoring or histological evidence of esophagitis on an esophageal biopsy. Dental erosion has been shown to be associated with GERD as an atypical complication and has the potential to be a marker of GERD. The purposes of this study were to compare the frequency and patterns of dental erosion in children and adolescents with and without histologic esophagitis. METHODS: Twenty-five subjects were recruited from patients scheduled for an upper gastrointestinal endoscopy. Information regarding potential GERD symptoms, food habits, and dental hygiene habits were obtained. Intra-oral photographs were taken, and a dental exam for erosion was performed. The results of a standard biopsy taken from the lower third of the esophagus during an endoscopy were used to divide subjects into either the control group or the GERD group (i.e. those with histologic esophagitis). RESULTS: Twenty-two subjects yielded 586 evaluable teeth. No significant difference was found between frequency or erosion patterns of those with and without histologic esophagitis. Dental erosions were more frequent in primary teeth. CONCLUSIONS: Dental erosions do not appear to be associated with histologic esophagitis indicative of GERD.


Subject(s)
Esophagitis/pathology , Tooth Erosion/etiology , Child , Cross-Sectional Studies , Diet , Esophagitis/complications , Esophagoscopy , Esophagus/pathology , Gastroesophageal Reflux/complications , Gastroesophageal Reflux/pathology , Humans , Oral Hygiene
3.
Pediatrics ; 125(3): 547-53, 2010 Mar.
Article in English | MEDLINE | ID: mdl-20123769

ABSTRACT

OBJECTIVE: To assess the effect of Web-based training (WBT) on resident knowledge of preventive oral health and compare the addition of hands-on training (HOT) to WBT on resident skills, confidence opinions, and practice. METHODS: Pediatric residents participated in a WBT on preventive oral health. After the WBT, subjects were randomly assigned to receive HOT by a dentist (WBT + HOT) or WBT alone. All subjects were assessed on knowledge by a pretest/posttest questionnaire and assessed on skills in the performance of an oral examination by direct observation. Residents' confidence regarding oral health counseling and their opinions about the importance of the incorporation of oral health into the well-child visit were measured by surveys that used a Likert scale. Residents' change in practice was assessed by a retrospective chart audit. RESULTS: Fifty-six residents were included in the analysis (WBT + HOT: 29; WBT: 27). Resident knowledge improved after the WBT from 69% to 81% (95% confidence interval [CI]: 9%-15%). Overall skills improved in the WBT + HOT group participants compared with those in the WBT group (87% vs 73%; difference: 14% [95% CI: 1.2%-26.6%]). Seventy-nine percent of participants in the WBT + HOT group compared with 44% of those in the WBT provided follow-up instructions (relative risk: 0.56 [95% CI: 0.35-0.89]). Resident opinions regarding incorporating preventive oral health into the well-child visit decreased by 33% in the WBT + HOT group compared with 11% in the WBT group (95% CI: 2%-43%). There were no significant differences in confidence regarding preventive oral health and practice between the groups. CONCLUSIONS: Both instructional methods resulted in increases in knowledge, efficacy, and practice of preventive oral health. The addition of hands-on training by a dental provider increased the overall skills of oral examination, but this increase was largely a result of the provision of follow-up instruction.


Subject(s)
Dental Caries/prevention & control , Internet , Internship and Residency/methods , Oral Health , Pediatrics/education , Child , Female , Humans , Male , Retrospective Studies
4.
Pain Manag Nurs ; 6(1): 10-7, 2005 Mar.
Article in English | MEDLINE | ID: mdl-15917740

ABSTRACT

The purpose of this study was to determine the adequacy of the alternate forms reliability of three versions of the Oucher pain scale. Because the original large-sized posters were unwieldy for use by nurses with children in clinical settings, it became necessary to reduce it in size. To determine whether the resulting tools were psychometrically equivalent to the original versions of the Oucher, this study was undertaken. In a group of 3- to 12-year-old children who underwent surgical or dental procedures ( n = 137), scores were obtained after the procedure on small and large versions of the Oucher. The order of presentation of the two different Ouchers was randomized. Findings revealed that correlation coefficients between the scores provided for the small and large versions of the Oucher were strong, positive, and significant for the Caucasian, African-American, and Hispanic versions in 3- to 12-year-old children. These results provided evidence of the adequacy of the alternate forms reliability of these scales.


Subject(s)
Black or African American/ethnology , Hispanic or Latino/ethnology , Pain Measurement/methods , Pain, Postoperative/diagnosis , Pain, Postoperative/ethnology , White People/ethnology , Age Factors , Ambulatory Surgical Procedures/adverse effects , Attitude to Health/ethnology , Child , Child Behavior/ethnology , Child, Preschool , Facial Expression , Female , Hospitals, Pediatric , Humans , Male , Midwestern United States , Nursing Assessment/methods , Nursing Assessment/standards , Nursing Evaluation Research , Pain Measurement/nursing , Pain Measurement/standards , Pain, Postoperative/physiopathology , Psychology, Child , Psychometrics , Sensitivity and Specificity
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