Change in waist circumference and lifestyle habit factors as a predictor of metabolic risk among middle-aged and elderly Japanese people: population-based retrospective 10-year follow-up study from 2008 to 2017.

BACKGROUND: Waist circumference (WC) increases more than body mass index (BMI) over time. This study investigated the change in WC among middle-aged and elderly Japanese people for 10 years, and its relationship with lifestyle and lipid metabolism factor. METHODS: Health checkup data and lifestyle habits of a retrospective cohort of 745 people aged 40-65 years who underwent health checkups at least three times between 2008 and 2017 were analyzed. Information of Lifestyle habits about smoking history, regular exercise, alcohol intake skipping breakfast was collected using a self-administered questionnaire. Participants who were taking medications for diabetes, hyperlipidemia, or hypertension were excluded from analyses. Longitudinal associations between the change in WC and lifestyle habit factors with adjustments for sex, age, and WC at the start of health checkups were assessed using generalized linear models. RESULTS: Regardless of lifestyle, body weight (BW) decreased 0.8 kg (p < 0.001) for women, 0.9 kg (p = 0.003) for men, WC increased 0.8 cm (p = 0.007) for women, 0.2 cm (p = 0.657) for men. In addition, serum triglycerides and high- and low-density lipoprotein levels estimated 10 years later revealed that increased WC ratios also exacerbated the respective blood sample data. CONCLUSION: Both men and women showed an increase in WC regardless of BW changes, and the increase in WC worsened lipid metabolism. For the middle-aged and elderly, whose WC increases over time, it will be more important to take notice of their WC than BW or BMI for effective health checkups.

The Trends of Medical Care Expenditure with Adjustment of Lifestyle Habits and Medication; 10-Year Retrospective Follow-Up Study.

In Japan, the prevention of lifestyle-related diseases is the most important issue for the optimization of medical expenditure. This study aimed to analyze the impact of lifestyle and medication status on medical expenditure. Health checkup data and medical expenditure records of a retrospective cohort of 1463 people aged between 40 and 65 years old who underwent specific health checks at least three times between 2008 and 2017 were analyzed. Regression analysis was performed with medical expenditure as the dependent variable and age, gender, waist ratio, medication status, and lifestyle habits as independent variables using a Tobit model. Focusing on the factors that increase medical expenditure, the regression coefficients of age, medication status, weight gain of 10 kg or more since the age of 20, and walking more than 1 h per day were 0.048 (95% CI 0.04 to 0.06), 1.020 (95% CI 0.88 to 1.16), 0.210 (95% CI 0.06 to 0.36), and -0.208 (95% CI -0.35 to -0.07), respectively. The estimate of 5-year cumulative medical expenditure showed that those with walking habits without medication had the lowest medical expenditure. The result of this study suggests that walking more than 1 h a day may lower health expenditure in the general population.