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1.
J Laryngol Otol ; 124(9): 1003-6, 2010 Sep.
Article in English | MEDLINE | ID: mdl-20426887

ABSTRACT

AIM: To demonstrate diagnostic imaging of an extremely rare presentation of bilateral narrow duplication of the internal auditory canal. CASE REPORT: An adolescent boy with profound sensorineural hearing loss presented for hearing rehabilitation. Imaging studies (i.e. multidetector computed tomography and magnetic resonance imaging) clearly demonstrated bilateral duplication of the internal auditory canals, with narrowing of the lower canals, unilateral cochlear and vestibular dysplasia, bilateral superior semicircular canal malformation, and bilateral absence of the posterior semicircular canals. CONCLUSION: To our knowledge, this is only the third such case described in the literature. Considering that the vestibulocochlear nerve has been unable to be demonstrated in almost all cases of duplicated internal auditory canal (unilateral and bilateral), our case supports the hypothesis that vestibulocochlear nerve aplasia or hypoplasia leads to internal auditory canal stenosis. We consider this rare presentation of bilateral narrow duplication of the internal auditory canal to represent a contraindication for cochlear implantation.


Subject(s)
Ear, Inner/abnormalities , Hearing Loss, Bilateral/congenital , Hearing Loss, Sensorineural/congenital , Temporal Bone/abnormalities , Vestibulocochlear Nerve/abnormalities , Acoustic Impedance Tests , Adolescent , Audiometry , Cochlear Implantation , Contraindications , Ear, Inner/diagnostic imaging , Humans , Magnetic Resonance Imaging , Male , Rare Diseases/diagnosis , Tomography, X-Ray Computed/methods
2.
Br J Radiol ; 77(921): 724-7, 2004 Sep.
Article in English | MEDLINE | ID: mdl-15447956

ABSTRACT

Cytomegalovirus (CMV) pneumonia is one of the most common pulmonary complications after bone marrow transplantation (BMT). We describe the high resolution CT (HRCT) findings of 13 patients with CMV pneumonia diagnosed after allogenic BMT. The study included 13 consecutive patients who developed CMV pneumonia after BMT and who had HRCT of the chest performed within 24 h of the onset of symptoms. HRCT scans were reviewed by two radiologists who assessed pattern and distribution of findings. There were nine male and four female patients, ranging from 9 years to 56 years of age (mean age 33 years). BMT was performed for treatment of chronic myelogenous leukaemia (54%), severe aplastic anaemia (23%), acute myelogenous leukaemia (15%) and Fanconi's anaemia (8%). The time elapsed until diagnosis ranged from +18 days to +405 days (median of 54 days, mean +81.6 days). The predominant patterns of abnormality on HRCT scans were ground-glass opacities (69%), small centrilobular nodules (69%) and air-space opacities (54%). The abnormalities were distributed in the central and peripheral zones of the lungs in six cases, only in the periphery in four cases, and only in the central zone in three cases. In all cases the lung lesions were bilateral, and asymmetry was observed in seven cases. The authors conclude that the most common HRCT findings in patients with CMV pneumonia after BMT consist of bilateral asymmetric ground-glass, air-space opacities and small centrilobular nodules.


Subject(s)
Bone Marrow Transplantation/adverse effects , Cytomegalovirus Infections/diagnostic imaging , Pneumonia, Viral/diagnostic imaging , Tomography, X-Ray Computed/methods , Adolescent , Adult , Child , Cytomegalovirus Infections/etiology , Female , Humans , Male , Middle Aged , Pneumonia, Viral/etiology , Transplantation, Homologous
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