ABSTRACT
PURPOSE: To analyze the characteristics and prognostic factor of penile cancer, we retrospectively reviewed the clinicopathological data of patients with a diagnosis of penile cancer treated. PATIENTS AND METHODS: The records of 59 patients (median age 66, ranged from 47 to 91) with squamous cell carcinoma of the penis reffered between April 1988 and January 2006 were reviewed. The importance of tumor size and stage, differentiation, type of infiltration, vascular invasion, patient age, lymph node metastasis, distant metastasis and type of therapy were assessed using univariate and multivariate analyses. RESULTS: After a mean follow up of 37.7 months, 13 cases (22.0%) died of cancer and 5-year survival was 67.4%. Multivariate analysis demonstrated that, type of operation (p = 0.0471, Hazard ratio 3.364), vascular invasion (p = 0.0014, Hazard ratio 5.921) were associated with survival. CONCLUSION: Vascular invasion and type of operation were related to survival. Our findings indicate that correct pathological diagnosis and appropriate treatment may lead to prolonged survival.
Subject(s)
Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/therapy , Penile Neoplasms/pathology , Penile Neoplasms/therapy , Aged , Aged, 80 and over , Analysis of Variance , Carcinoma, Squamous Cell/diagnosis , Carcinoma, Squamous Cell/secondary , Combined Modality Therapy , Follow-Up Studies , Humans , Lymphatic Metastasis , Male , Middle Aged , Neoplasm Invasiveness , Neoplasm Staging , Penile Neoplasms/diagnosis , Prognosis , Retrospective StudiesABSTRACT
A 66-year-old man was admitted to our hospital with left flank pain. Drip infusion pyelography (DIP) and abdominal computed tomography (CT) showed urinary extravasation. Magnetic resonance imaging (MRI) and retrograde pyelography (RP) demonstrated stenosis of the ureter. Left nephroureterectomy was performed. Histopathological examination showed poorly differentiated adenocarcinoma, located in the ureteral wall with intact mucosa and adventitia. After the operation, sigmiod colon carcinoma was pointed out by colon fiberscope, and sigmoidectomy was performed.