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Gan To Kagaku Ryoho ; 46(13): 2143-2145, 2019 Dec.
Article in Japanese | MEDLINE | ID: mdl-32156859

ABSTRACT

Chemoradiotherapy(CRT)for locally recurrent rectal cancer can shrink the tumor and permit R0 resection; however, its effectiveness and safety have not been established. Herein, we report a case of a 60s man with locally recurrent rectal cancer invading the surrounding organs who was administered CRT followed by R0 laparoscopic-assisted abdominoperineal resection( APR). Local recurrence was detected 11 months after laparoscopic-assisted low anterior resection(pT3N0M0, pStage Ⅱ). After tumor shrinkage by CRT(capecitabine 3,000mg/day plus 45 Gy/25 Fr), laparoscopic-assisted APR was performed. The pathological findings showed a pathological complete response(pCR). The patient had not experienced recurrent disease at 6 months after the second surgery. CRT may improve the prognosis of patients with locally recurrent rectal cancer, especially those with possibly unresectable tumors.


Subject(s)
Rectal Neoplasms , Chemoradiotherapy , Humans , Male , Neoplasm Recurrence, Local , Neoplasm Staging , Prognosis , Rectal Neoplasms/therapy , Treatment Outcome
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