[Chemotherapy: its repercussions on fertility and potency]. / Chemioterapia: sue ripercussioni sulla fertilità e sulla potenza sessuale.

In the past twenty years, combined therapeutic regimens have improved the survival rare in many human tumors. Chemotherapy plays a significant role on this outcome. Unfortunately, many chemotherapeutic agents have adverse effects on gonadal function. The Authors examine the pathophysiology of gonadal damage in male diagnosed with cancer and treated with chemotherapeutic agents. Infertility and/or impotence can occur on these patients: the relationships between chemotherapy and tumors, towards seminal and sexual dysfunctions, are focused. Moreover, current possibilities to preserve recovery both fertility and sexual functions and discussed.

[Local complications of papaverine-induced erection: follow-up at 7 years]. / Complicanze locali della farmacoerezione con papaverina: follow-up a 7 anni.

127 patients whose age was from 36 to 68 years old, affected by coeundi impotence, have been started to pharmaco-injection. 44 of these patients practised self-injection for 3 years: 25% once a week, 60% fortnightly and 15% once a month. The 60% of first group patients showed a certain fibrotic plaque between the 11th and the 13th month. At the end of the first year two patients with significative penile deviation underwent to corporoplasty. The 40% (6 patients) that made injection every 15-20 days showed fibrotic plaque between the 22nd and the 32nd month. At the third year two more patients underwent to corporoplasty. The 9 patients that made pharmacoerection monthly, showed plaque after almost 38 months. Only 11 patients have been using self-injection from about 7 years. At the half of the fifth year all patients presented multiple plaques and the 95% showed significant bends. At the end of the sixth year, 3 patients with serious bend, not to permit sexual intercourses, underwent to corporoplasty, having refused prosthesis. The anatomo-pathologic situation of the cavernous bodies has showed an heavy fibrosis, hipertrophy of smooth muscle and many perivascular phlogistic infiltrates.

The surgical correction of varicocele: multidisciplinary study on semen evaluation and prognostic factors for fertility.

The seminal pattern was studied in a group of 52 patients before and six months after sclerotherapy of varicocele. In this series, we studied the differences in clinical and seminal characteristics between the group that succeeded in obtaining a pregnancy and the group that remained infertile after 1 year follow-up. The difference in pregnancy rate is discussed between the operated group and a control group of pz, who refused any form of surgery, after 1 year follow-up.