ABSTRACT
Radial scar is a confusing lesion of the breast which represent a premalignant lesion. It looks like a tubular carcinoma but histologically we can see two rows of cells in tubules. Mammographically there are some typical but not specific signs: (1) the presence of the central radiolucency, (2) the presence of radial long thin spicules, (3) varying appearance in different projection, (4) radiolucent linear structures parallel to spicules, and (5) abscence of palpable lesion or skin changes. All these signs make the "black star" appearance. Authors reanalyzed 21 from 26 woman with the radial scar diagnosis. Aim of our study was to investigate the different morphologic changes in view of differential diagnosis, frequency and potential prognostic importance of the different lesions. According to our findings we can conclude that the radial scar is unpalpable, subclinical lesion which can be seen on mammography but the final diagnosis is histological.
Subject(s)
Breast Neoplasms/diagnosis , Carcinoma/diagnosis , Cicatrix/diagnosis , Adult , Aged , Breast/pathology , Breast Diseases/diagnosis , Breast Diseases/pathology , Breast Neoplasms/pathology , Carcinoma/pathology , Cell Proliferation , Cicatrix/pathology , Female , Humans , Mammography/methods , Middle Aged , Precancerous Conditions , Radiography/methods , Retrospective StudiesABSTRACT
UNLABELLED: Breast phyllodes tumors (FT) belong the fibroapitelial group of breast tumors arising in terminal ductulo-lobular unit (TDLU). Their incidence do not exceed 1% of all breast tumors. Biologicaly they can be divided into benign, borderline and malignant group. Incomplete tumor excision can be the reason for local reccurence. Malignant form of FT metastazise hematogenous most often in the lung. There is no uniform surgical opinion about the treatment FT. METHODS: We analyzed histopathology features of 319 FT of the breast surgicaly removed on Departement of surgery Institut of oncology and radiology of Serbia between 1.1.1985.-31.12.1994. Retrospective study of surgical treatment 84 patients with FT of the breast (69 benign, 4 borderline and 11 malignant) and 5 year follow up after surgery we analysed. RESULTS: local reccurence after surgery was found in 17 (20,2 %) patients(14 benign , 2 borderline and 1 malignant FT), pulmonary metastases in 6 (7,1%) patients with malignant FT. DFI was 21,3 months for local reccurences and 25,1 months for pulmonary metastases. DFS for al forms of FT was 71 % (p =0,7104) in 5-year follow up. CONCLUSION: According to biological behavior we propose wide excision for benign and borderline forms and simple mastectomy for malignant FT, and voluminous benign and borderline forms. Axillary disection is not necessary because lymphatic spread of malignant FT is unfrequent.
Subject(s)
Breast Neoplasms/surgery , Phyllodes Tumor/surgery , Breast Neoplasms/pathology , Female , Humans , Neoplasm Recurrence, Local , Phyllodes Tumor/secondaryABSTRACT
Authors analysed 15 cases with visceral metastasis of melanoma. In eight cases the primary was unknown but in seven cases the data about primary was known. From 15 patients 10 were male and 5 female. All metastases were in abdominal cavity (liver-3, abdominal lymph nodes-4. stomach-2, bowel-4, omentum-1, spleen-1, oesophagus-1, adrenal-2 cases. In one case metastatic deposit was in brain and in one case i the vertebral body. In 6 cases visceral metastases were in more than one location.
