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1.
Neurol Res ; 32(8): 879-85, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20223107

ABSTRACT

OBJECTIVES: This study aims to demonstrate and test a new surgical tool which is designed and manufactured in our institution for neurosurgical operations. The device is referred as 'air jet dissector'. METHODS: After fabrication of the device, we tested it on 32 New Zealand rabbits. The effectiveness of the device was compared with a well-known ultrasonic aspirator (CUSA) in an experimental design of cranial corticotomies. Dissection quality, intracranial hemorrhage, edema formation and astroglial and microglial reactions were compared for both devices. RESULTS: Regarding post-operative edema formation and intracranial hemorrhage, the air jet dissector was found superior to the CUSA system. Additionally, the pre-operative comfort of the device was also better than the CUSA. CONCLUSION: In our opinion, this new design has a future in neurosurgical operating rooms. Further refinements and experimental testing is required.


Subject(s)
Compressed Air/trends , Creativity , Dissection/instrumentation , Dissection/trends , Equipment Design/trends , Animals , Blood Loss, Surgical/prevention & control , Dissection/methods , Equipment Design/methods , Male , Rabbits , Random Allocation
2.
J Clin Neurosci ; 12(4): 445-8, 2005 May.
Article in English | MEDLINE | ID: mdl-15925779

ABSTRACT

Topical hemostatic agents are widely and safely used in neurosurgery. The purpose of this study was to compare and analyse the early tissue reactions to two hemostatic agents, oxidized regenerated cellulose and gelatin sponge, in rabbit brain by magnetic resonance imaging and histopathologic sections. Bilateral identical parenchymal lesions were made in the frontal regions of each hemisphere in 13 rabbits. Hemostasis was achieved using oxidized regenerated cellulose or gelatin sponge, one agent being used on each side. Cranial magnetic resonance imaging was performed 24 h postoperatively and there was no statistical difference in edema formation at the site of the lesions. Histopathologic examinations indicated that pericapillary edema and endothelial distortion were common in both groups but that there was additional tissue degeneration evident in the regions where gelatin sponge had been used. Oxidized regenerated cellulose seemed to cause greater tissue distortion in magnetic resonance images than gelatin sponge but in contrast, histological examination of lesions in which oxidized regenerated cellulose had been used revealed less tissue degeneration than histopathologic examinations of lesions in which gelatin sponge had been used.


Subject(s)
Brain Injuries , Cellulose , Gelatin Sponge, Absorbable , Hemostatics , Animals , Brain Injuries/diagnosis , Brain Injuries/metabolism , Brain Injuries/pathology , Magnetic Resonance Imaging/methods , Male , Rabbits
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