ABSTRACT
Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma (STS) in children and adolescents. In Spain the annual incidence is 4.4 cases per million children < 14 years. It is an uncommon neoplasm in adults, but 40% of RMS are diagnosed in patients over 20 years of age, representing 1% of all STS in this age group. RMS can appear anywhere in the body, with some sites more frequently affected including head and neck, genitourinary system and limbs. Assessment of a patient with suspicion of RMS includes imaging studies (MRI, CT, PET-CT) and biopsy. All patients with RMS should receive chemotherapy, either at diagnosis in advanced or metastatic stages, or after initial resection in early local stages. Local control includes surgery and/or radiotherapy depending on site, stage, histology and response to chemotherapy. This guide provides recommendations for diagnosis, staging and treatment of this neoplasm (AU)
Subject(s)
Humans , Positron Emission Tomography Computed Tomography/methods , Rhabdomyosarcoma/therapy , Rhabdomyosarcoma/epidemiology , Rhabdomyosarcoma/pathology , Combined Modality Therapy , Incidence , Spain/epidemiologyABSTRACT
Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma (STS) in children and adolescents. In Spain the annual incidence is 4.4 cases per million children < 14 years. It is an uncommon neoplasm in adults, but 40% of RMS are diagnosed in patients over 20 years of age, representing 1% of all STS in this age group. RMS can appear anywhere in the body, with some sites more frequently affected including head and neck, genitourinary system and limbs. Assessment of a patient with suspicion of RMS includes imaging studies (MRI, CT, PET-CT) and biopsy. All patients with RMS should receive chemotherapy, either at diagnosis in advanced or metastatic stages, or after initial resection in early local stages. Local control includes surgery and/or radiotherapy depending on site, stage, histology and response to chemotherapy. This guide provides recommendations for diagnosis, staging and treatment of this neoplasm.
Subject(s)
Positron Emission Tomography Computed Tomography/methods , Practice Guidelines as Topic/standards , Rhabdomyosarcoma/therapy , Child , Combined Modality Therapy , Humans , Incidence , Rhabdomyosarcoma/diagnostic imaging , Rhabdomyosarcoma/epidemiology , Rhabdomyosarcoma/pathology , Spain/epidemiologySubject(s)
Arthritis, Infectious/diagnostic imaging , Leukocyte Transfusion , Leukocytes , Osteomyelitis/diagnostic imaging , Radiopharmaceuticals , Technetium Tc 99m Exametazime , Adult , Aged , Aged, 80 and over , Arthritis, Infectious/etiology , Arthritis, Infectious/physiopathology , Bone Plates/adverse effects , Chemotaxis, Leukocyte , Child, Preschool , Diabetic Foot/complications , Diabetic Foot/diagnostic imaging , Diabetic Foot/surgery , Discitis/diagnostic imaging , Female , Humans , Joint Prosthesis/adverse effects , Male , Middle Aged , Osteomyelitis/etiology , Osteomyelitis/physiopathology , Postoperative Complications/diagnostic imaging , Prosthesis-Related Infections/diagnostic imaging , Radionuclide Imaging , Spondylitis/diagnostic imaging , Surgical Wound Infection/diagnostic imagingABSTRACT
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