Interaction force between two finite-size charged particles in weakly ionized plasma.

The results of numerical studies of the interaction forces between two finite-size charged spherical conductive particles embedded into weakly ionized strongly collisional isothermal plasma-like medium are presented. The studies are performed for the case of particles with fixed electric charge under the assumption that particles do not absorb electrons and ions from the surrounding plasma (colloidal particles) as well as for particles charged by plasma currents (grains). In the first case the Poisson-Boltzmann model was used and in the second the dynamics of grain charging is described in the drift-diffusion approximation. It is shown that at the large distances the interaction force between colloidal particles has the Debye screened asymptotic while for the grains the Coulomb-like behavior is observed. The dependence of the grain charge collected due to the plasma particle absorption on the distance between two grains is studied. The possibility of introducing effective Coulomb description of finite-size grain interaction in weakly ionized strongly collisional plasma is discussed.

Is a one-week course of triple anti-Helicobacter pylori therapy sufficient to control active duodenal ulcer?

BACKGROUND: Triple therapy currently forms the cornerstone of the treatment of patients with Helicobacter pylori-positive duodenal ulcer. AIM: To establish whether prolonged antisecretory therapy is necessary in patients with active duodenal ulcer. METHODS: A total of 77 patients with H. pylori-positive duodenal ulcer were included in a prospective, controlled, double-blind study. All patients received a 7-day treatment with omeprazole 20 mg b.d., clarithromycin 500 mg b.d. and amoxicillin 1000 mg b.d. Patients in the omeprazole group underwent an additional 14-day therapy with omeprazole 20 mg; patients in placebo group received placebo. Endoscopy was performed upon inclusion in the study and after 3 and 8 weeks. RESULTS: Seventy-four patients were eligible for a per protocol analysis after 3 weeks, and 65 after 8 weeks. After 3 weeks, the healing rate was 89% in the omeprazole group and 81% in the placebo group (P=0.51). After 8 weeks, the ulcer healed in 97% of the patients in the total group (95% CI: 92.7-100%). H. pylori was eradicated in 88% of patients in the omeprazole group and in 91% in the placebo group (P=1.0). No statistically significant differences between the groups were found in ulcer-related symptoms or in ulcer healing. CONCLUSION: In patients with H. pylori-positive duodenal ulcer, a 7-day triple therapy alone is sufficient to control the disease.