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Am J Trop Med Hyg ; 88(3): 578-82, 2013 Mar.
Article in English | MEDLINE | ID: mdl-23339200

ABSTRACT

Cutaneous leishmaniasis is endemic in Salta, the northwestern province of Argentina. We describe an outbreak involving five recreational hunters whose exposure was limited to several hours in a residual patch of primary forest. All patients presented with typical cutaneous lesions after a mean incubation period of 59 days (range 15-78), and one developed simultaneous mucosal involvement. Polymerase chain reaction analysis of lesions confirmed Leishmania (V.) braziliensis as the etiologic agent in three cases. All patients were cured with anti-Leishmania treatment. Entomologic surveys in the transmission area revealed a predominance of Lutzomyia neivai. This outbreak report confirms a microfocal transmission pattern of tegumentary leishmaniasis in the Americas and based on a well-determined exposure, allows the determination of incubation times for leishmaniasis caused by Leishmania braziliensis.


Subject(s)
Disease Outbreaks , Leishmaniasis, Cutaneous/epidemiology , Adult , Amphotericin B/therapeutic use , Animals , Antiprotozoal Agents/therapeutic use , Argentina/epidemiology , Deoxycholic Acid/therapeutic use , Drug Combinations , Environmental Exposure , Humans , Insect Vectors , Leishmaniasis, Cutaneous/drug therapy , Psychodidae , Trees
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