1.
Chem Commun (Camb)
; 58(64): 9022-9025, 2022 Aug 09.
Article
in English
| MEDLINE
| ID: mdl-35875940
ABSTRACT
The aggregation-sensitive chiroptical (ECD and RROA) output, provided by enantiopure (3S,3'S)-astaxanthin, was used to investigate and control the assembling processes of the carotenoid in Pluronic F-127 nanoparticles. The process of carotenoid J-aggregation inside nanocarriers is interfered with by the formation of kinetically stabilized H1 self-assemblies outside the micelles. Nanocarriers with encapsulated stable J-aggregates provide controlled release of carotenoid molecules to primary murine adipocytes.