[Biochemical basis of varying nystatin resistance of Saccharomyces cerevisiae and Candida maltosa mutants]. / Biokhimicheskie osnovy razlichnoi ustoichivosti k nistatinu u mutantov drozhzhei Saccharomyces cerevisiae i Candida maltosa.

Six groups of nystatin resistant mutants of C. maltosa and of haploid and diploid Saccharomyces cerevisiae strains were obtained with the help of genetic and biochemical analysis. It has been shown that every group of the mutants was characterized by a specific level of resistance to nystatin. The dependence of the resistance level upon sterol content has been established. It has been shown that the more the structure of the sterol present differed from ergosterol the higher was the resistance level. The results obtained in vivo permit to make conclusions about the role of different functional groups of sterol molecule in the interaction with nystatin.

[Unextended and extended selective proximal vagotomy in the treatment of chronic uncomplicated duodenal ulcer]. / Primenenie nerasshirennoi i rasshirennoi selektivnoi proksimal'noivagotomii v lechenii khronicheskoi neoslozhnennoi iazvennoi bolezni dvenadtsatiperstnoi kishki.

Comparison of the results of selective proximal vagotomy (SPV) and extended selective proximal vagotomy (eSPV) in identical groups of patients with chronic uncomplicated peptic ulcer of the duodenum showed that early postoperative complications are encountered more frequently after eSPV. The decrease in gastric secretion is similar, delayed evacuation is more marked after eSPV. The ulcerous defect healed within equal periods, the late results were the same. In view of the above stated, the authors claim that patients with moderately increased gastric secretion (acidity below 45 mEq/hour) should be preferably treated by SPV; the indications for eSPV need further study.

[Use of beta-adrenoblockaders in the therapy of the syndromes accompanying acute myocardial infarct]. / Ispol'zovanie beta-adrenoblokatorov v terapii nekotorykh sindromov, soprovozhdaiushchikh ostryi infarkt miokarda.

The use of beta-adrenoblockers in patients with acute myocardial infarction, accompanied by hypertension and hyperdynamia, leads to normalization of the arterial pressure, of parametres of haemo- and cardiodynamics, to a decrease of the degree of ischaemia of the damaged myocardium and to an increase of the heart work efficacy.

[Anti-arrhythmic and hemodynamic effects of visken and glucagon in rhythm disorders in the acute phase of myocardial infarct]. / Antiaritmicheskie i gemodinamicheskie éffekty viskena i gliukagona pri narusheniiakh ritma v ostroi faze infarkta miokarda.

Combination of the beta-adrenergic blocking agent visken with glucagon in the acute period of myocardial infarction possesses higher antiarrhythmic activity with a negligible cardiodepressive effect as compared to that of isolated administration of visken and leads to a decrease in the excessive production of catecholamines and glucocorticoids in the blood.