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1.
Rev Clin Esp ; 200(4): 193-7, 2000 Apr.
Article in Spanish | MEDLINE | ID: mdl-10857402

ABSTRACT

BACKGROUND: Multiple studies suggest that ultrasound measurement of the bone can be a rapid, cheap, and radiation-free alternative to determine the fracture risk. In this paper the ultrasound measurement of the bone was performed among 288 postmenopausal women, and the influence of gynecologic history and factors related to lifestyle on the obtained values was examined. PATIENTS AND METHODS: One hundred nineteen healthy postmenopausal women and 169 women with previous osteoporotic fractures were included in the study. Both weight and height were determined and a clinical questionnaire was administered to assess factors related to bone mineral density. The values of broadband ultrasound attenuation (BUA) and speed of sound (SOS) were obtained with a contact ultrasound analyzer. RESULTS: Among women without fractures the mean BUA and SOS values (64.1 [14.9] and 1,601.1 [34.5], respectively) were significantly higher than mean BUA (48.8 [17.3]) and SOS (1,573 [57.8]) values among women with fractures (p < 0.001). Using the logistic regression analysis for predicting fracture risk, the model that suited best was that including BUA (OR = 0.668 [0.544-0.818]), age (OR = 1.102 [1.055-1.151]), age at postmenopause (OR = 0.794 [0.731-0.862]) and height (OR = 0.932 [0.883-0.983]). The area under the curve for this model was 0.871. CONCLUSIONS: BUA and SOS values are lower among women with osteoporotic fractures. The fracture risk can be predicted by means of a model including the variables BUA, age, postmenopausal age, and height.


Subject(s)
Bone and Bones/diagnostic imaging , Fractures, Spontaneous/epidemiology , Fractures, Spontaneous/etiology , Osteoporosis, Postmenopausal/complications , Osteoporosis, Postmenopausal/diagnostic imaging , Aged , Aged, 80 and over , Female , Humans , Middle Aged , Predictive Value of Tests , Regression Analysis , Risk Assessment , Risk Factors , Ultrasonography
2.
Rev. clín. esp. (Ed. impr.) ; 200(4): 193-197, abr. 2000.
Article in Es | IBECS | ID: ibc-6856

ABSTRACT

Fundamento. Múltiples estudios sugieren que la medición ultrasónica del hueso puede ser una alternativa rápida, barata y sin radiación para determinar el riesgo de fracturas. En este trabajo hemos realizado medición ultrasónica del hueso en 288 mujeres posmenopáusicas, analizando la influencia de la historia ginecológica y de factores relacionados con el estilo de vida en los valores obtenidos. Pacientes y métodos. Se incluyeron 119 mujeres postmenopáusicas sanas y 169 con fracturas osteoporóticas previas. Se midió peso y talla y se realizó un cuestionario clínico para valoración de los factores relacionados con la densidad mineral ósea. Se obtuvieron las medidas de atenuación ultrasónica de banda ancha (BUA) y velocidad del sonido (VS) con un analizador ultrasónico de contacto. Resultados. En las mujeres sin fracturas los valores medios de BUA y VS (64,1 [14,9] y 1.601,1 [34,5], respectivamente) fueron significativamente superiores a los de BUA (48,8 [17,3]) y VS (1.573,6 [57,8]) en las mujeres con fracturas (p < 0,001). En el análisis de regresión logística para predicción del riesgo de fracturas el modelo que mejor se ajustaba era el que incluía BUA (OR = 0,668 [0,544-0,818]), edad (OR = 1,102 [1,055-1,151]), edad de la menopausia (OR = 0,794 [0,731-0,862]) y talla (OR = 0,932 [0,883-0,983]).El área bajo la curva receiver operating characteristic (ROC) de este modelo fue 0,871. Conclusiones. Los valores de BUA y VS son inferiores en las mujeres con fracturas osteoporóticas. El riesgo de fractura se puede predecir a través de un modelo que incluya las variables BUA, edad, edad de la menopausia y talla (AU)


Subject(s)
Middle Aged , Aged, 80 and over , Aged , Female , Humans , Risk Factors , Osteoporosis, Postmenopausal , Risk Assessment , Regression Analysis , Bone and Bones , Fractures, Spontaneous , Predictive Value of Tests
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