ABSTRACT
PURPOSE OF REVIEW: Periocular sebaceous cell carcinoma is a rare malignancy that is often misdiagnosed leading to increased morbidity and mortality. This review aims to describe current knowledge on the disease to aid clinicians in timely diagnosis and treatment. RECENT FINDINGS: New research has shown that the diagnosis of sebaceous cell carcinoma can be aided with immunohistochemical stains. A revision in the American Joint Committee on Cancer staging system incorporates new tumor size classifications in the staging of eyelid carcinomas. Wide local excision and Mohs micrographic surgery continue to represent the standard of care for initial treatment of localized disease. SUMMARY: The current review highlights diagnostic and treatment modalities to allow clinicians to make timely diagnosis and tailor treatment plans for individual patient presentations.
Subject(s)
Adenocarcinoma, Sebaceous , Diagnostic Errors , Diagnostic Techniques, Ophthalmological , Eyelid Neoplasms , Sebaceous Gland Neoplasms , Skin Neoplasms/diagnosis , Adenocarcinoma, Sebaceous/diagnosis , Adenocarcinoma, Sebaceous/epidemiology , Adenocarcinoma, Sebaceous/surgery , Eyelid Neoplasms/diagnosis , Eyelid Neoplasms/epidemiology , Eyelid Neoplasms/surgery , Global Health , Humans , Mohs Surgery , Morbidity/trends , Sebaceous Gland Neoplasms/diagnosis , Sebaceous Gland Neoplasms/epidemiology , Sebaceous Gland Neoplasms/surgery , Survival Rate/trendsSubject(s)
Adenocarcinoma, Scirrhous/secondary , Breast Neoplasms/pathology , Enophthalmos/etiology , Orbital Neoplasms/secondary , Adenocarcinoma, Scirrhous/complications , Adenocarcinoma, Scirrhous/diagnosis , Aged , Biopsy , Breast Neoplasms/complications , Diagnosis, Differential , Enophthalmos/diagnosis , Enophthalmos/surgery , Female , Humans , Magnetic Resonance Imaging , Neoplasm Metastasis , Ophthalmologic Surgical Procedures , Orbit/pathology , Orbital Neoplasms/complications , Orbital Neoplasms/therapy , Radiotherapy, AdjuvantABSTRACT
PURPOSE: To evaluate demographics, characteristics, and outcomes of open-globe injuries (OGIs) in motor vehicle accidents (MVAs). METHODS: Retrospective chart review of patients with OGIs related to MVAs that presented to University Hospital, Newark, from 2000 to 2012. RESULTS: Twenty-five patients were identified; the average age of the patients was 33.3 years old (range, 5-75). The majority of patients (64 %) were males. The 25 vehicles comprised 24 automobiles and one motorcycle. Ten patients (40 %) wore seatbelts, and five (20 %) did not wear seatbelts. The seatbelt status was not documented in the remaining cases. Ethanol was documented as a contributing factor in five of the accidents. In terms of open-globe classification, 15 OGIs (60 %) were ruptures, and five (20 %) were penetrating injuries; three (12 %) had intraocular foreign bodies. Ten eyes (40 %) had a final VA of 20/400 or worse. Fourteen eyes (56 %) achieved a final VA of 20/200 or better; seven eyes (28 %) achieved a final VA of 20/40 or better. CONCLUSION: Fifty-six percent of eyes with an open-globe injury related to MVAs achieved a final VA of 20/200 or better in this series. No eyes developed endophthalmitis.
