ABSTRACT
We have revised the concept of pseudolymphoma, some of its classifications and its differences with the malignant lymphoma, which sometimes are only an evolution, not existing other elements of judgement. We publish the summary of ten lymphocytoma cutis cases studied by us, which we believe are the paradigm of the B pseudo-lymphoma due to the clinical and hystological controversy in our patients. One of them shifted to malignant lymphoma after 30 years of evolution as a lymphocytoma. Under the denomination of lymphocytoma we believe should be included a group of not well defined process, of unknown etiology, described in literature under the names of "Spiegler-Fendt Sarcoid", "lymphadenosis benigna cutis", "benign lymphocytic reticulosis" and "lymphocytic infiltration of Jessner" all of them with clinical evidences of papulo-tuberous lesion, covered by a yellowish to brownish red erythematous skin with the appearance of "orange skin" with no ulcers and usually located on the head (nose, forehead and scalp) or in any other part of the skin, looking sometimes, like the malignant lymphoma. Histologically characterized by a dense lymphocytic reaction proliferation; polymorphous with a diffuse or nodular pattern, characteristic in B pseudolymphoma. We should establish the differences between at least two clinical forms: the one of single lesion, of multiple lesions in the same area, called therefore single and multiple regional form, each one with its own characteristics and with certain clinical and hystological relations: single-Nodular and multiple-diffuse. The existence of important adenopathies in the multiple form, its clinics, its long evolution and its developing in malignant lymphoma in one of our cases makes us especially aware of this form and we strongly recommend to keep a lifetime control.
Subject(s)
Lymphoma, Non-Hodgkin/pathology , Skin Neoplasms/pathology , Adult , Aged , B-Lymphocytes , Diagnosis, Differential , Female , Head and Neck Neoplasms/diagnosis , Head and Neck Neoplasms/pathology , Humans , Lymphoma, Non-Hodgkin/classification , Lymphoma, Non-Hodgkin/diagnosis , Male , Middle Aged , Neoplasms, Multiple Primary/pathology , Skin Neoplasms/diagnosis , Terminology as TopicABSTRACT
We presented a patient with a deforming and necrotizing syndrome of the nasal pyramid. The histopathology demonstrated a lymphoma. The original works of Weiss are related. The diseases is characterized by: ecotaxis of the nasal pyramid, localized persistency during a long time, malaise in advanced studies and sensibility to radiations. We proposed the name linfoma histiocitico maligno nasal de Weiss and consider it as a autonomous entity.
Subject(s)
Granuloma, Lethal Midline/pathology , Nose Diseases/pathology , Adult , Female , Granuloma, Lethal Midline/diagnosis , Granuloma, Lethal Midline/radiotherapy , Humans , Nose Diseases/diagnosis , Nose Diseases/radiotherapy , Pregnancy , Pregnancy ComplicationsABSTRACT
La dermatosis ampollar cronica benigna del nino es clinica e histopatologicamente una afeccion muy similar al penfigoide ampollar.Su diferenciacion puede realizarse unicamente con estudios inmunopatologicos. Presenta dos patronen es inmunofluorescencia directa: 1) negatividad para inmunoglobulinas y complemento, y 2) deposito de IgA de disposicion lineal. Presentamos dos observaciones: la primera, nina de 5 anos, con respuesta optima a corticoides y sulfonas, inmunopatologia negativa; la segunda, varon de 6 anos, cuya dermatosis evoluciona ininterrumpidamente desde el sexto dia del nacimiento. Solo respondia a dosis altas de corticoides. La inmunofluorescencia directa fue negativa
Subject(s)
Skin Diseases, Vesiculobullous , Complement System Proteins , Fluorescent Antibody Technique , ImmunoglobulinsABSTRACT
Se realiza estudio clinico, histopatologico, patogenico del glioma nasal. Tumoracion benigna de facil diagnostico. Se contraindica la biopsia, propiciandose el estudio de la pieza quirurgica. Se presenta una observacion en un nino que presenta el glioma acantonado en su sitio tipico. Se clasifica como forma cutanea o extranasal, no se comprobo conexion cerebral
Subject(s)
Glioma , Nose NeoplasmsABSTRACT
La dermatosis ampollar cronica benigna del nino es clinica e histopatologicamente una afeccion muy similar al penfigoide ampollar.Su diferenciacion puede realizarse unicamente con estudios inmunopatologicos. Presenta dos patronen es inmunofluorescencia directa: 1) negatividad para inmunoglobulinas y complemento, y 2) deposito de IgA de disposicion lineal. Presentamos dos observaciones: la primera, nina de 5 anos, con respuesta optima a corticoides y sulfonas, inmunopatologia negativa; la segunda, varon de 6 anos, cuya dermatosis evoluciona ininterrumpidamente desde el sexto dia del nacimiento. Solo respondia a dosis altas de corticoides. La inmunofluorescencia directa fue negativa
Subject(s)
Skin Diseases, Vesiculobullous , Complement System Proteins , Fluorescent Antibody Technique , ImmunoglobulinsABSTRACT
Se realiza estudio clinico, histopatologico, patogenico del glioma nasal. Tumoracion benigna de facil diagnostico. Se contraindica la biopsia, propiciandose el estudio de la pieza quirurgica. Se presenta una observacion en un nino que presenta el glioma acantonado en su sitio tipico. Se clasifica como forma cutanea o extranasal, no se comprobo conexion cerebral
Subject(s)
Glioma , Nose NeoplasmsABSTRACT
Preceded by a brief commentary about the clinical characteristics of actinic prurigo, the qualities of anantifibrinolytic medication and its possible machanism of action in allergic conditions and atopias are analysed. An earlier experience with five familiar cases of actinic prurigo given 1 g of tranexamic acid or 3 g E. ACA, within a period of three months has been effective remarkally exceeding the results obtained with other therapeutic agents. The proposed therapeutic scheme may or may not be, modified, according to the response to the response of each individual case.
Subject(s)
Antifibrinolytic Agents/therapeutic use , Facial Dermatoses/etiology , Prurigo/drug therapy , Sunlight , Adolescent , Adult , Aminocaproic Acid/therapeutic use , Dermatitis, Atopic/drug therapy , Dermatitis, Atopic/genetics , Drug Evaluation , Drug Therapy, Combination , Facial Dermatoses/drug therapy , Facial Dermatoses/genetics , Female , Humans , Male , Prurigo/etiology , Prurigo/genetics , Tranexamic Acid/therapeutic useABSTRACT
Three cases of Bullosis Diabeticorum, entity described by Rocca and Pereyra, are reported by the authors. The review of the published literature after the original article shows the importance of recognizing these symptoms for the diagnosis of an occult diabetes. The most outstanding features of the studied cases were: a) the bullosis traumatica present in the 3 observations; b) the finding of an unknown diabetes in two of the three patients; c) the association with stellate pseudoscars. The histopathologic findings were similar in all three patients.
Subject(s)
Blister/etiology , Diabetes Complications , Adult , Aged , Female , HumansABSTRACT
Two cases of naevus lipomatosus superficialis (Hoffmann and Zurhelle) are described by the authors. The main clinical characteristics and histological peculiarities are reviewed. Both cases were disseminated and had typical localisation (pelvic area). The histological examination showed ectopic adipocytes in the dermis. The authors mare a reference to the different hypotheses on the pathogenesis of these lesions.
Subject(s)
Lipoma/pathology , Skin Neoplasms/pathology , Adolescent , Diagnosis, Differential , Female , HumansABSTRACT
A patient with palatal hemangioma was subjected to study and the general characteristics of buccal hemangioma are analyzed. Their infrequent occurrence being remarkable. Maxillar angiomas have a reserved prognosis not only because of their histologic malignancy but also because of the threat of incoercible hemorrhage with the removal of dentures. Therefore radical surgical intervention or eventual radiotherapy is indicated.
Subject(s)
Hemangioma , Palatal Neoplasms , Adult , Diagnosis, Differential , Hemangioma/diagnostic imaging , Hemangioma/pathology , Humans , Male , Maxillary Neoplasms/diagnosis , Mouth Neoplasms/diagnosis , Palatal Neoplasms/diagnostic imaging , Palatal Neoplasms/pathology , RadiographyABSTRACT
A bibliographic review of a new subject-pemphigus with eosinophilic spongiosis accomplished: Three clinical courses are recognized: a) pemphigus in its initial phase, b) pemphigus markedly seborrheic, which presents during its evolution, some morphologic anomalies, c) pemphigus that appear like an authentic Duhring in its initial phase and during part of its evolution. On studying the histopathology three aspects are observed; 1) pure eosinophilic spongiosis with two modalites: diffuse or vesiculate; 2) mixed eosinophilic spongiosis and, 3) alternate eosinophilic spongiosis. The review report the study of this new observation and discusses the nosological situation as well as its pausible causation.
Subject(s)
Dermatitis Herpetiformis/pathology , Pemphigus/pathology , Adult , Biopsy , Diagnosis, Differential , Eosinophils , Humans , MaleABSTRACT
3 cases of cocidiomycosis observed in the province of Mendoza (Argentina) are described by the authors. The study of the endemic cocidiomycosis in Argentina and the ecological aspects of this disease in Mendoza are studied by the authors.
Subject(s)
Coccidioidomycosis/pathology , Skin/pathology , Adolescent , Argentina , Biopsy , Child, Preschool , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Mouth Mucosa/pathologyABSTRACT
A case of true mielinic neuroma is described. An exhaustive review of the literature on this subject, basically of the Bolande article is carried out by the authors. The mielinic neuromata are a partial aspect of the complexe neuro-crestopathic syndromes associating the cutaneous lesions to: 1) Medullary tyroid carcinoma, 2) pheocromocytoma and 3) neurofibromatous lesions. The observation related by the authors shows: 1) Ehlers-Danlos disease (not described previously), 2) skeletal abnormalities, 3) medullary tyroid carcinoma and 4) pheochromocytoma symptoms.
Subject(s)
Ehlers-Danlos Syndrome/pathology , Mouth Neoplasms/pathology , Neuroma/pathology , Pheochromocytoma/pathology , Thyroid Neoplasms/pathology , Adolescent , Autopsy , Female , Humans , Macroglossia , Mouth Mucosa/pathology , Myelin Sheath/pathologyABSTRACT
A review of the different types of angiokeratoma in particular of the angiokeratoma neviformis circunscritus is made by the authors. After differential diagnosis and pathogeny of this lesion the authors suggest that the best is excision surgical followed by grafting. Description of a case.
Subject(s)
Angiokeratoma , Aged , Angiokeratoma/diagnosis , Diagnosis, Differential , Humans , MaleABSTRACT
Clinical study and bibliographic review of the lymphomatoid papulosis (Macaulay-1968) and parapsoriasis varioliformis acute (Mucha-1916). A personal case is reported after a review of nosological location of these diseases and the variable prognosis. The authors reach the following conclusions: 1st) From the clinical point of view the small number of lesions in the lymphomatoid papulosis bring about a different clinical picture from that of parapsoriasis varioliformis acuta in here usually there is a considerable number of lesions. 2nd) There are concomitant lesions of parapsoriasis gutata in parapsoriasis varioliformis and none of the type in lymphomatoid papulosis. 3rd) Protracted course in lymphomatoid papulosis and short lived eruption in the parapsoriasis varioliformis acuta. 4th) From the histological point of view denser and atypical infiltrate in cases of parapsoriasis varioliformis.
