ABSTRACT
Sensitivity tests to different antimicrobial agents were performed in 290 strains of S. aureus isolated from healthy population and from patients with various infectious diseases. Resistance to penicillin G varied from 80 to 97% and beta-lactamase production was demonstrated in all strains with CMI greater than 1 microgram/ml. Resistance to other drugs was variable: gentamicin 29.4%, erythromycin 24.5% and rifampicin 12%. All strains were sensitive to isoxazolyl penicillins with CMI less than 1 microgram/ml. There was no difference in the sensitivity pattern to antibiotics between strains isolated from community or from hospital acquired infections with reference to the antimicrobial resistance pattern.
Subject(s)
Anti-Bacterial Agents/pharmacology , Staphylococcus aureus/drug effects , Adult , Carrier State/microbiology , Child , Cross Infection/microbiology , Dicloxacillin/pharmacology , Erythromycin/pharmacology , Gentamicins/pharmacology , Humans , Penicillin G/pharmacology , Penicillin Resistance , Rifampin/pharmacology , Staphylococcal Infections/microbiology , Staphylococcus aureus/isolation & purificationABSTRACT
Se efectuo la sensibilidad a diferentes antimicrobianos de 290 cepas de S.aureus, obtenidas de poblacion sana y enfermos con patologia diversa. Los porcentajes de resistencia a la penicilina G en los grupos estudiados variaron de 80 a 97 por ciento y se demostro produccion de betalactamasas en todas las cepas con CMI>1 ug/ml para este antibiotico. En el caso de gentamicina, eritromicina y rifampicina los porcentajes de resistencia fueron de 29,4, 24,5 y 12 por ciento respectivamente. Todas las cepas fueron sensibles a dicloxacilina, el 94,2 por ciento tuvieron CMI< 1 ug/ml y no encontramos diferencia en el patron de sensibilidad a los antibioticos probados entre las cepas procedentes de comunidad y las de adquisicion hospitalaria
