ABSTRACT
Alrededor de 5 % de los tumores del estroma gastrointestinal (GIST) se localizan en el recto. Cuando se encuentran localmente avanzados, el tratamiento neoadyuvante con imatinib ha demostrado buenos resultados para reducir el volumen de este tipo de tumores. Se presenta el caso de un paciente con diagnóstico de GIST rectal gigante, al que se le administró neoadyuvancia con imatinib y, posteriormente, se sometió a resección anterior baja con anastomosis coloanal. Es imprescindible que la evaluación y el tratamiento sean multidisciplinarios en los GIST rectales, para tratar de obtener los mejores resultados ante esta entidad tan poco frecuente, poder evitar la comorbilidad asociada y practicar cirugías menos agresivas tras una buena reacción terapéutica al imatinib
Less than 5% of gastrointestinal stromal tumors (GIST) are located at the rectum. When these tumors are locally advanced, neoadjuvant therapy with imatinib has shown good results, reducing its volume. We present the case of a patient with a giant rectal GIST tumor, who underwent neoadjuvant imatinib therapy, and posterior low anterior resection with coloanal anastomosis. In rectal GIST tumors it is essential the multidisciplinary evaluation and treatment, in order to obtain the best possible results in this rare entity. After a good response to the treatment with imatinib, aggressive surgeries can be avoided, along with the associated morbidity that comes with it
Subject(s)
Humans , Rectal Neoplasms , Gastrointestinal Stromal Tumors , Imatinib Mesylate , Surgical OncologyABSTRACT
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Subject(s)
Humans , Male , Middle Aged , Colonic Pseudo-Obstruction/complications , Colonic Pseudo-Obstruction/surgery , Colonic Pseudo-Obstruction , Anastomosis, Surgical/methods , Anastomosis, Surgical/trends , Anastomosis, Surgical , Respiratory Insufficiency/complications , Respiratory Insufficiency/surgery , Respiratory Insufficiency , Megacolon/complications , Megacolon , Colonoscopy/methods , ColonoscopyABSTRACT
OBJECTIVE: To report a clinical case of penile metastasis of a rectal adenocarcinoma. METHODS: We report the case of a 78-year-old male with a clinical history of rectum adenocarcinoma. The management included an anterior rectum-resection and postoperative combination of neoadjuvant chemo and radiotherapy. Eight months after the operation, a painful solitary nodular lesion on the glans penis was diagnosed. We performed a needle biopsy (Tru-cut). RESULTS: Histological examination confirmed metastasis of the rectal tumour. We performed partial penectomy. CONCLUSIONS: The incidence of penile metastasis is extremely low. In a large number of cases the primary tumour is localized in the genito-urinary tract, less likley they originate from other organs. The treatment, depending to each case, is mostly palliative due to the poor prognosis of disease.
Subject(s)
Adenocarcinoma/secondary , Penile Neoplasms/secondary , Rectal Neoplasms/pathology , Adenocarcinoma/therapy , Aged , Combined Modality Therapy , Humans , Male , Penile Neoplasms/therapyABSTRACT
OBJETIVO: Aportar un caso de metástasis peneana de adenocarcinoma de recto. MÉTODOS: Presentamos el caso clínico de un varón de 78 años con tumoración de recto, localizado en el tercio medio. Se realizó una resección anterior de recto con combinación de quimioradioterapia neodayuvante. A los 8 meses de la intervención presenta un nódulo solitario doloroso con ulceración central en el glande. Realizamos biopsia de la lesión por aguja fina (Tru-cut). RESULTADO: Estudio de anatomía patológica confirma metástasis de adenocarcinoma intestinal compatible con tumor primario de recto. Tras descartar otras lesiones metastásicas mediante el TAC, realizamos penectomía parcial. CONCLUSIONES: La incidencia de las metástasis peneanas es muy baja. Este tipo de lesiones proceden, sobre todo, de los tumores primarios de los órganos genitourinarios y raras veces de otros órganos. El tratamiento es variado dependerá de cada caso y habitualmente paliativo debido a mal pronóstico de la enfermedad
OBJECTIVE: To report a clinical case of penile metastasis of a rectal adenocarcinoma. METHODS: We report the case of a 78-year-old male with a clinical history of rectum adenocarcinoma. The management included an anterior rectum-resection and postoperative combination of neoadjuvant chemo and radiotherapy. Eight months after the operation, a painful solitary nodular lesion on the glans penis was diagnosed. We performed a needle biopsy (Tru-cut). RESULTS: Histological examination confirmed metastasis of the rectal tumour. We performed partial penectomy. CONCLUSIONS: The incidence of penile metastasis is extremely low. In a large number of cases the primary tumour is localized in the genito-urinary tract, less likley they originate from other organs. The treatment, depending to each case, is mostly palliative due to the poor prognosis of disease
