ABSTRACT
OBJECTIVE: To investigate whether there is an association between suicidal ideation (SI) and allergic diseases in adults. METHODS: This was a comparative cross-sectional study involving individuals ranging from 20 to 50 years of age recruited from a university hospital in the city of Guadalajara, Mexico. We included patients with a confirmed diagnosis of allergic asthma, those with a confirmed diagnosis of allergic rhinitis, and healthy controls. All subjects completed the Beck Depression Inventory-II (BDI-II), which includes an item that evaluates the presence of suicidal thoughts or desires within the last two weeks, in order to identify SI. RESULTS: The sample comprised 115 patients with allergic asthma, 111 patients with allergic rhinitis, and 96 healthy controls. The number of individuals identified with SI in the three groups were, respectively, 17 (14.8%), 13 (11.7%), and 8 (8.3%). Regarding the presence of SI, no statistically significant association was found in the allergic asthma group (OR = 1.98; 95% CI: 0.78-4.64; p = 0.154) or in the allergic rhinitis group (OR = 1.46; 95% CI: 0.58-3.68; p = 0.424) when they were compared with the control group. However, the presence of depression was associated with SI in the three groups: allergic asthma (OR = 12.36; 95% CI: 2.67-57.15; p = 0.001); allergic rhinitis (OR = 6.20; 95% CI: 1.66-23.14; p = 0.006); and control (OR = 21.0; 95% CI: 3.75-117.36; p < 0,001). CONCLUSIONS: In comparison with the control group, no association was found between SI and the groups with allergic diseases. In contrast, there was association between SI and depression in the three groups.
Subject(s)
Asthma/psychology , Depressive Disorder/psychology , Rhinitis, Allergic/psychology , Suicidal Ideation , Adult , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Psychiatric Status Rating Scales , Risk Factors , Severity of Illness Index , Young AdultABSTRACT
ABSTRACT Objective: To investigate whether there is an association between suicidal ideation (SI) and allergic diseases in adults. Methods: This was a comparative cross-sectional study involving individuals ranging from 20 to 50 years of age recruited from a university hospital in the city of Guadalajara, Mexico. We included patients with a confirmed diagnosis of allergic asthma, those with a confirmed diagnosis of allergic rhinitis, and healthy controls. All subjects completed the Beck Depression Inventory-II (BDI-II), which includes an item that evaluates the presence of suicidal thoughts or desires within the last two weeks, in order to identify SI. Results: The sample comprised 115 patients with allergic asthma, 111 patients with allergic rhinitis, and 96 healthy controls. The number of individuals identified with SI in the three groups were, respectively, 17 (14.8%), 13 (11.7%), and 8 (8.3%). Regarding the presence of SI, no statistically significant association was found in the allergic asthma group (OR = 1.98; 95% CI: 0.78-4.64; p = 0.154) or in the allergic rhinitis group (OR = 1.46; 95% CI: 0.58-3.68; p = 0.424) when they were compared with the control group. However, the presence of depression was associated with SI in the three groups: allergic asthma (OR = 12.36; 95% CI: 2.67-57.15; p = 0.001); allergic rhinitis (OR = 6.20; 95% CI: 1.66-23.14; p = 0.006); and control (OR = 21.0; 95% CI: 3.75-117.36; p < 0,001). Conclusions: In comparison with the control group, no association was found between SI and the groups with allergic diseases. In contrast, there was association between SI and depression in the three groups.
RESUMO Objetivo: Investigar se existe associação entre ideação suicida (IS) e doenças alérgicas em adultos. Métodos: Estudo transversal comparativo envolvendo indivíduos com idade entre 20 e 50 anos recrutados em um hospital universitário da cidade de Guadalajara, México. Foram incluídos pacientes com diagnóstico confirmado de asma alérgica, aqueles com diagnóstico confirmado de rinite alérgica e controles saudáveis. Todos os sujeitos preencheram o Beck Depression Inventory-II (BDI-II), que inclui um item que avalia a presença de pensamentos ou desejos suicidas nas últimas duas semanas, a fim de identificar IS. Resultados: A amostra foi composta por 115 pacientes com asma alérgica, 111 pacientes com rinite alérgica e 96 controles saudáveis. O número de indivíduos identificados com IS nos três grupos foi de 17 (14,8%), 13 (11,7%) e 8 (8,3%), respectivamente. Quanto à presença de IS, não foi encontrada associação estatisticamente significativa no grupo asma alérgica (OR = 1,98; IC95%: 0,78-4,64; p = 0,154) ou no grupo rinite alérgica (OR = 1,46; IC95%: 0,58-3,68; p = 0,424) quando os mesmos foram comparados com o grupo controle. No entanto, a presença de depressão apresentou associação com IS nos três grupos: asma alérgica (OR = 12,36; IC95%: 2,67-57,15; p = 0,001); rinite alérgica (OR = 6,20; IC95%: 1,66-23,14; p = 0,006); e controle (OR = 21,0; IC95%: 3,75-117,36; p < 0,001). Conclusões: Em comparação com o grupo controle, não foi encontrada associação entre IS e os grupos com doenças alérgicas. Por outro lado, houve associação entre IS e depressão nos três grupos.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Young Adult , Asthma/psychology , Depressive Disorder/psychology , Suicidal Ideation , Rhinitis, Allergic/psychology , Psychiatric Status Rating Scales , Severity of Illness Index , Cross-Sectional Studies , Risk FactorsABSTRACT
BACKGROUND: Hypovitaminosis D has been associated with various chronic diseases such as infections, autoimmune diseases, chronic obstructive pulmonary disease, cancer and asthma Objective: The objective at hand is to determine the prevalence of vitamin D (VD) insufficiency and deficiency in adults with allergic asthma. OBJECTIVE: Objective: The objective at hand is to determine the prevalence of vitamin D (VD) insufficiency and deficiency in adults with allergic asthma. METHODS: Through a cross-sectional study, we analyzed corresponding data amongst 135 patients. VD concentration was categorized as sufficient (≥ 30 ng/mL), insufficient (21-29 ng/mL), and deficient (≤ 20 ng/mL). The level of VD deficiency was measured through chemo-luminescence. We estimated the prevalence of VD alterations and their respective confidence intervals at 95 % (CI 95 %). RESULTS: Within the analyzed population, there were 99/135 women (73.3 %); the mean age was 34.5 ± 10.3 years. The mean concentration of VD was 17.9 ± 6.9 ng/mL and the median was 17 ng/mL. The prevalence of VD insufficiency and deficiency was 25.2 % (CI 95 %, 18.6-33.2 %) and 71.1 % (CI 95 %, 62.9-78.1 %), respectively; VD concentrations ≤ 10 ng/mL had 13.3 % (CI 95 %, 8.5-20.2 %) and ≥ 30 ng/mL at 3.7 % (CI 95 %: 1.4-8.6 %). When we contrasted the men to the women, the median concentration of VD did not differ significantly (16 ng/mL vs. 18 ng/mL, p = 0.71). CONCLUSION: In this study, patients with allergic asthma had distinctively reduced VD concentration levels; future research will determine if and how VD affects the severity of asthma.
Antecedentes: La hipovitaminosis D ha sido asociada con diversas enfermedades crónicas como infecciones, enfermedades autoinmunes, enfermedad pulmonar obstructiva crónica, cáncer y asma. Objetivo: Determinar la prevalencia de insuficiencia y deficiencia de vitamina (VD) en adultos con asma alérgica. Métodos: Estudio transversal en el que se analizaron los datos de 135 pacientes. La concentración de VD fue categorizada en suficiente (≥ 30 ng/mL), insuficiente (21-29 ng/mL) y deficiente (≤ 20 ng/mL). La concentración de VD se midió por quimioluminiscencia. Se estimaron las prevalencias de las alteraciones de la VD y sus respectivos intervalos de confianza a 95 % (IC 95 %). Resultados: En la población analizada, 99 fueron mujeres (73.3 %), con edad media de 34.5 ± 10.3 años. La concentración media de VD fue 17.9 ± 6.9 ng/mL (mediana de 17 ng/mL). La prevalencia de insuficiencia y deficiencia de VD fue de 25.2 % (IC 95 %, 18.6-33.2 %) y 71.1 % (IC 95 %, 62.9-78.1 %), respectivamente; las concentraciones de VD ≤ 10 ng/mL representaron 13.3 % (IC 95 %, 8.5-20.2 %) y ≥ 30 ng/mL, 3.7 % (IC 95 %, 1.4-8.6 %). Al contrastar hombres y mujeres, la concentración mediana de VD no difirió significativamente (16 ng/mL versus 18 ng/mL, p = 0.71). Conclusiones: En este estudio, los pacientes con asma alérgica tuvieron concentraciones de VD notoriamente disminuidas. Con futuras investigaciones se podrá evaluar el papel de la VD en la gravedad del asma.
