1.
Am J Surg Pathol
; 20(2): 239-44, 1996 Feb.
Article
in English
| MEDLINE
| ID: mdl-8554114
ABSTRACT
We report a case of primary embryonal rhabdomyosarcoma of long bone, presenting as a lytic destructive bone tumor in the right femoral diaphysis of a 7-year-old girl. To our knowledge, this is only the third report of this entity. The neoplasm was a pure embryonal rhabdomyosarcoma with numerous rhabdomyoblasts. Immunohistochemistry confirmed the diagnosis: The cells were reactive with antibodies directed against desmin, muscle-specific actin, and myoglobin. No other neoplastic mesenchymal component was present within the tumor. Although rare, primary rhabdomyosarcoma, along with Ewing's tumor and osteosarcoma, should be considered in the differential diagnosis of malignant bone tumors in childhood.
Subject(s)
Bone Neoplasms/pathology , Femur , Rhabdomyosarcoma, Embryonal/pathology , Actins/analysis , Bone Neoplasms/chemistry , Bone Neoplasms/diagnostic imaging , Child , DNA, Neoplasm/analysis , Desmin/analysis , Female , Flow Cytometry , Humans , Immunoenzyme Techniques , Magnetic Resonance Imaging , Myoglobin/analysis , Radiography , Rhabdomyosarcoma, Embryonal/chemistry , Rhabdomyosarcoma, Embryonal/diagnostic imaging
2.
J Bone Joint Surg Am
; 69(7): 1096-9, 1987 Sep.
Article
in English
| MEDLINE
| ID: mdl-3654703