ABSTRACT
OBJECTIVE: To compare the effectiveness of nasal continuous positive airway pressure (NCPAP) cycling with continuous NCPAP in the successful weaning of preterm infants of 25(0)-28(6) wk gestation to nasal prongs. METHODS: A total of 30 infants with a gestational age (GA) of 25(0)-28(6) wk, ventilated for respiratory distress syndrome (RDS) and extubated to NCPAP were eligible for the study. They were randomized to NCPAP cycling [Group A: cycling between NCPAP of 4 cm and 1 liter per minute (LPM) of nasal prongs] or to continuous NCPAP at 4 cm of H2O (Group B). Primary outcome was successful weaning off NCPAP to nasal prongs at the end of 72 h of the intervention and remaining off NCPAP for the next 72 h. RESULTS: The demographic characteristics were similar in both the groups. Infants were randomized to Group A (n = 13) and Group B (n = 17). The primary outcome was not significantly different between the groups (successful weaning to nasal prongs: 31 vs. 41 %; p 0.71). CONCLUSIONS: In this pilot, feasibility study there were no differences in the rates of successful weaning of NCPAP to nasal prongs using either cycling NCPAP or continuous NCPAP in preterm infants. A need exists for a large randomized controlled trial (RCT) to determine the role of cycling NCPAP on neonatal outcomes.
Subject(s)
Continuous Positive Airway Pressure/methods , Feasibility Studies , Female , Humans , Infant, Newborn , Infant, Premature , Male , Pilot Projects , Respiratory Distress Syndrome, Newborn/therapySubject(s)
Acquired Immunodeficiency Syndrome/prevention & control , Anti-HIV Agents/therapeutic use , HIV Seropositivity/drug therapy , HIV Seropositivity/transmission , Condoms , Family Characteristics , Female , Heterosexuality , Humans , Male , Medication Adherence , Patient Education as Topic , Risk Factors , United Kingdom/epidemiology , Viral LoadABSTRACT
Although renal cysts occur in children less frequently than adults, they are not as rare as once believed. Eight children with simple renal cysts are reviewed. The diagnostic and radiographic studies in each patient showed characteristic findings. A nonoperative diagnosis of simple renal cyst in a child usually can be made with confidence and surgical confirmation is not necessary.
