[Intracytoplasmic sperm injection for treatment of male infertility].

The results of 84 consecutive couples who underwent 94 cycles of in-vitro fertilization (IVF) augmented with intracytoplasmic sperm injection (ICSI) were analyzed. Inclusion criteria were previous total failed fertilization or unsuitable sperm parameters for conventional IVF. The rate of diploid fertilization was 61,7%; the implantation rate per embryo was 12,0% and the ongoing pregnancy rate per transfer was 30,0%. None of the sperm parameters of the original or processed semen sample were correlated with ICSI outcome. Conversely, female age and basal serum concentrations of follicle stimulating hormone (FSH) had a significant impact on implantation and pregnancy rates. ICSI has become a very successful therapy in overcoming different types of male infertility.

[The role of ultrasound scanning of endometrium in the superovulation stimulation program during in vitro fertilization and embryo transfer].

The intensive introduction of in vitro fertilization and embryo transfer into the clinical practice of sterility treatment has conditioned the necessity of developing reliable methods of control of the response of ovaries to the application of gonadotropic hormones for stimulating superovulation. There is not sufficient data about prognostic value of ultrasound scanning of structure of endometrium before or after the day of HCG administration in IVF cycles. Several authors have revealed differences in endometrial structure between the women with or without pregnancy. According to the results of our studies, the endometrium thickness has a rather positive prognostic index for evaluating the possibility of the occurrence of pregnancy. Therefore, it is a highly informative ultrasound criterion for making a decision of the completion of superovulation induction and introduction of the embryo transfer and, consequently, makes an important contribution to the in vitro fertilization procedure optimization.