Regeneración ósea en alvéolos dentarios de terceros molares mandibulares empleando plasma rico en plaquetas en pacientes fumadores / Bone regeneration in mandibular third molar dental sockets of smokers using platelet rich plasma

Objetivo. El propósito del trabajo fue evaluar la regeneración ósea en alvéolos dentarios empleando como coadyuvante PRP en pacientes fumadores. Materiales y método. Estudio de intervención cuasiexperimental; se asignaron 2 grupos de estudio, uno experimental y otro de control; se realizó exodoncia a los 2 grupos de los dientes 38 y 48. Al grupo control no se aplicó PRP y al experimental se le aplicó PRP con el método de una centrifugación en el alvéolo del diente 38 y PRP con doble centrifugación en alvéolo del diente 48; se realizaron controles radiográficos a los 8, 30 y 60 días después de la cirugía para evaluar la densidad ósea. Se realizó análisis estadístico descriptivo univariado, bivariado y prueba t de Student. Resultados. Hicieron parte del estudio 19 sujetos, el 52,6% de ellos fueron de sexo masculino, al estudiar la densidad ósea en los 3 controles radiográficos del grupo experimental en el alvéolo del diente 38 y 48, no se encontraron diferencias estadísticamente significativas (p > 0,05), pero sí una leve mejoría en la cicatrización del alvéolo 48 donde se empleó PRP con el método de doble centrifugación. Al comparar los controles radiográficos del grupo control con los del grupo experimental se encontraron valores estadísticamente significativos en el grupo que se le aplicó PRP con el método de una o doble centrifugación (p<0,05). Conclusión. El proceso de regeneración ósea es más favorable en los pacientes fumadores que se les aplica PRP que en aquellos que no se les aplica. No se observó una diferencia estadísticamente significativa en el proceso de regeneración ósea aplicando PRP con el método de una y doble centrifugación

Objective. The aim of this study was to evaluate bone regeneration in the dental sockets of smokers using platelet-rich-plasma (PRP) as an adjuvant. Materials and method. A quasi-experimental intervention study of two groups (experimental and control) in whom teeth number 38 and 48 were extracted. PRP was not applied in the control group, but it was applied in the experimental group using the single centrifugation method in the socket of tooth 38, and with double-centrifugation PRP being applied in the socket of tooth 48. Radiography follow-up was performed at 8, 30, and 60 days after the surgery in order to evaluate the bone density. A univariate and bivariate descriptive analysis and Student-t test were performed. Results. Of the 19 subjects that took part in the study, 52.6% were male. In the bone density study using the three radiographic controls at 8, 30, and 60 days, no statistically significant differences (P>.05) were found in the experimental group in the sockets of tooth 38 and 48, but there was a slight improvement in the healing of socket 48 where PRP was used with the method of double centrifugation. On comparing the follow-up x-rays of the control with those of the experimental group, statistically significant values were found in the group where PRP was applied using the single or double centrifugation method (P<.05). Conclusions. The bone regeneration process is more favourable in those smokers on whom PRP was applied than in those where it was not applied. No statistically significant difference was observed in the bone regeneration process applying PRP using the single or double centrifugation method

Bone healing of dental alveoli in smokers with platelet-rich plasma obtained using single or double centrifugation

Introduction: the habit of smoking alters the bone healing process, a problem to consider in oral surgery. objective: to evaluate the bone healing of dental alveoli with PRP obtained using single or double centrifugation in smokers. methodology: extraction of mandibular third molars was performed in a study population divided into smoking group (A), which had PRP applied with the protocol using a single centrifugation step (P1C) in the alveolus of tooth 38 and the protocol of double centrifugation (P2C) in alveolus of tooth 48; a smoking group(B), to whom no PRP was applied; and a non-smokers group (C) to whom PRP was applied obtained using P1C and P2C protocol. radiographic examination was performed at 8, 30 and 60 days post procedure. results: thirty patients met the criteria, 57 percent were female. when evaluating bone healing between the group of smokers and non-smokers, statistically significant differences were observed in the non-smoking group at 30 and 60 days, showing better results with the P2C protocol (p<0.005). statistically significant differences were found at 30 and 60 days (p<0.005), both with the P1C and P2C when comparing bone healing of group A and B. conclusions: bone healing in the alveoli of mandibular third molars that which PRP applied was higher in non-smoking patients, compared with the group of smokers. bone healing was better in patients smokers to whom PRP was applied than those without PRP treatment. regarding the method of obtaining PRP, bone healing was better when a double centrifugation protocol (P2C) was applied.