Subject(s)
Esophagitis, Peptic/surgery , Esophagus/surgery , Stomach/surgery , Vagotomy, Proximal Gastric , Vagotomy , Adult , Aged , Female , Follow-Up Studies , Humans , Male , Methods , Middle AgedABSTRACT
The gastroesophageal sphincter pressure (GESP) was studied before, during, and after food intake in 9 reflux esophagitis patients and 11 healthy controls. A significant decrease in GESP was observed 5, 10, and 30 min after the beginning of the meal in reflux esophagitis patients, contrasting with an increase during food intake in the control group. In the supine position GESP was significantly lower than in the sitting position in esophagitis patients, contrasting with a significantly higher GESP in the supine position in the control group. These results may explain why patients with gastroesophageal reflux often develop their symptoms during food intake and in the supine position.
Subject(s)
Eating , Esophagitis, Peptic/physiopathology , Esophagogastric Junction/physiopathology , Posture , Adult , Aged , Esophagitis, Peptic/etiology , Female , Humans , Male , Manometry , Middle Aged , PressureABSTRACT
Antroduodenal motility was studied before, during, and after food intake in patients with X-ray-negative dyspepsia and abnormal duodenal loop and in normals. No differences were observed between X-ray-negative dyspepsia and a proximally located abnormal duodenal loop. Patients with a distal duodenal anomaly had significantly higher food-stimulated duodenal activity than any of the other groups studied, whereas no differences were observed in antral motility.
Subject(s)
Duodenum/physiology , Dyspepsia/physiopathology , Eating , Gastrointestinal Motility , Adult , Duodenum/diagnostic imaging , Dyspepsia/diagnostic imaging , Female , Humans , Male , Middle Aged , RadiographyABSTRACT
The gastroesophageal sphincter pressure (GESP) was studied before, during, and after food intake in nine patients with abnormal duodenal loop (AD), six patients with a normal duodenum (controls), and seven healthy volunteers. In normal and control subjects a significant increase in GESP was observed during food intake, in contrast to a significant decrease in patients with AD. This may explain why patients with AD often develop symptoms when eating.
Subject(s)
Duodenum/abnormalities , Eating , Esophagogastric Junction/physiopathology , Adult , Aged , Esophagogastric Junction/physiology , Fasting , Female , Gastroesophageal Reflux/etiology , Humans , Male , Middle Aged , PressureABSTRACT
With the use of the perfused system for manometry, the resting pressure profile in the biliary tract system was investigated during operation in 15 patients with gallstones. Resting intraluminal pressure of the gallbladder was lower than the pressure in the common bile duct. At the level of the choledochoduodenal junction, a sphincter with phasic activity was demonstrated. A second high pressure zone was observed at the cysticocholedochal junction without phasic activity.
Subject(s)
Biliary Tract/physiopathology , Cholelithiasis/surgery , Pancreatitis/surgery , Adult , Aged , Common Bile Duct/physiopathology , Duodenum/physiopathology , Female , Gallbladder/physiopathology , Humans , Male , Manometry , Middle Aged , Pressure , Sphincter of Oddi/physiopathology , Urinary Bladder/physiopathologyABSTRACT
In 73 patients the occurrence of dyspeptic symptoms were correlated with the presence of a normal duodenal loop (29 patients) and an abnormal duodenal loop (44 patients). An abnormal duodenal loop was associated with a significantly higher incidence of symptoms provoked by meals, vomiting, regurgitation, heartburn, and the irritable bowel syndrome.
Subject(s)
Duodenum/abnormalities , Dyspepsia/etiology , Adult , Duodenum/diagnostic imaging , Female , Food , Humans , Male , Middle Aged , RadiographySubject(s)
Cholecystectomy , Cholelithiasis/physiopathology , Common Bile Duct/physiopathology , Gallstones/physiopathology , Pancreatic Ducts/physiopathology , Adenocarcinoma/physiopathology , Adult , Aged , Bile Duct Neoplasms/physiopathology , Common Bile Duct Neoplasms/physiopathology , Endoscopy , Female , Hepatic Duct, Common/physiopathology , Humans , Male , Manometry/methods , Middle Aged , Pancreatitis/physiopathology , Pressure , Sphincter of Oddi/physiopathologyABSTRACT
A total of 45 patients have undergone an Inkwell esophagogastrostomy after resection of a benign esophageal stricture. Nineteen patients were available for a long-term follow-up study, showing evidence of gastroesophageal reflux in 16 patients. Due to the high incidence of reflux and subsequent morphologic changes, there was a not negligible late disability. The Inkwell esophagogastrostomy can no longer be recommended in the treatment of an underlying reflux-induced lesion, strictures included.
Subject(s)
Esophageal Stenosis/surgery , Esophagoplasty/adverse effects , Gastroesophageal Reflux/etiology , Gastrostomy/adverse effects , Adolescent , Adult , Aged , Child , Child, Preschool , Esophagitis, Peptic/etiology , Female , Follow-Up Studies , Humans , Male , Middle Aged , Postoperative ComplicationsABSTRACT
Pressures in the Oddi sphincter and common bile duct were determined before, immediately after and several weeks after endoscopic papillotomy. Fifteen patients were included in the study. Significant decreases in Oddi sphincter and common bile duct pressures were found and the decrease in Oddi sphincter pressure was to some extent dependent upon the length of the papillotomy.
Subject(s)
Ampulla of Vater/physiopathology , Common Bile Duct/physiopathology , Gallstones/physiopathology , Sphincter of Oddi/physiopathology , Adult , Aged , Endoscopy , Female , Gallstones/surgery , Humans , Male , Middle Aged , PressureABSTRACT
Twenty-two patients with chronic upper dyspepsia but without ulcer disease were examined for gastro-oesophageal reflux and gastro-oesophageal sphincter pressure. Thirteen had an abnormal duodenal loop and nine a normal duodenum. An increased incidence of gastro-oesophageal reflux was found in patients with abnormal duodenal loop, whereas no differences were seen in the gastro-oesophageal sphincter pressure.
Subject(s)
Duodenum/abnormalities , Dyspepsia/physiopathology , Esophagogastric Junction/physiopathology , Gastroesophageal Reflux/physiopathology , Adult , Female , Humans , Hydrogen-Ion Concentration , Male , Manometry , Middle Aged , PressureABSTRACT
Resting common bile duct pressure and Oddi sphincter pressure were measured in 16 patients with common bile duct stones, 8 having in addition a juxta-ampullar diverticulum. Pressure measurements were performed with an infused catheter introduced through an endoscope under direct vision. No significant differences in fasting common bile duct pressures were observed between the two groups. The Oddi sphincter had a phasic activity, and the peak pressure was similar in both groups.
Subject(s)
Ampulla of Vater/physiopathology , Common Bile Duct/physiopathology , Diverticulum/physiopathology , Duodenal Diseases/physiopathology , Gallstones/physiopathology , Sphincter of Oddi/physiopathology , Aged , Diverticulum/complications , Duodenal Diseases/complications , Female , Gallstones/complications , Humans , Male , Manometry , Middle Aged , PressureABSTRACT
Basal and food-stimulated motility patterns were studied in seven patients with distal duodenal anomalies (DDA) and in seven controls. A discordant pressure pattern and a significantly higher frequency of pressure waves was observed in DDA both in the basal state and after food intake in comparison to controls. It is concluded that the shape of the duodenal loop can influence basal and food-stimulated motility patterns in the duodenum, and thereby probably also the transport mechanism through the duodenal loop.
