ABSTRACT
An 18-year-old boy with anoxic brain injury, suffering from severe psychomotor inhibition, tetrarigidity and dystonia, was treated with amantadine in order to ameliorate his symptoms. Neuropsychological tests showed improvement in motor and cognitive functions.
Subject(s)
Amantadine/therapeutic use , Antiparkinson Agents/therapeutic use , Brain Damage, Chronic/drug therapy , Brain Injuries/complications , Crush Syndrome/complications , Hypoxia, Brain/drug therapy , Parkinson Disease, Secondary/drug therapy , Activities of Daily Living/psychology , Adolescent , Amantadine/adverse effects , Antiparkinson Agents/adverse effects , Brain Damage, Chronic/etiology , Brain Injuries/drug therapy , Crush Syndrome/drug therapy , Follow-Up Studies , Humans , Hypoxia, Brain/etiology , Male , Neurocognitive Disorders/drug therapy , Neurocognitive Disorders/etiology , Neurologic Examination/drug effects , Neuropsychological Tests , Parkinson Disease, Secondary/etiologyABSTRACT
Silver-stained nucleolar organiser regions (AgNORs) were studied in 10 hyperplastic, 5 intra-epithelial neoplastic and 30 malignant prostatic lesions. Total AgNOR counts and types were compared with histological features. The total AgNOR count per nucleus was significantly higher (P less than 0.05) in prostatic intra-epithelial neoplasia (PIN) and adenocarcinoma compared with prostatic hyperplasia. In addition, satellite AgNORs predominated in hyperplasia, while medium-sized and large nucleoli with granular AgNORs were only observed in PIN and adenocarcinoma. The results indicate that, despite statistically significant differences, AgNOR counts are of no use for diagnosis of any single case in the groups studied, because of considerable overlap. AgNOR typing, however, may contribute to the differential diagnosis between benign and malignant lesions. We propose a new AgNOR typing system.
Subject(s)
Adenocarcinoma/ultrastructure , Nucleolus Organizer Region/ultrastructure , Prostate/pathology , Prostatic Neoplasms/ultrastructure , Humans , Hyperplasia , Male , Silver , Staining and LabelingABSTRACT
One hundred and eighty-eight and 167 first applications for disability pensions in 1981 and 1985 respectively were examined. Social parameters, diagnoses and the occurrence of alcohol and drug abuse were studied. There was a decrease in the number of male applicants and a small increase of female applicants from 1981 til 1985. Unskilled workers were overrepresented. Most applicants had been working within the last two years before the pension was awarded, and generally they had had long job periods. In 1985, had only 27% of the applicants under 50 attempted rehabilitation, and 12% had received social security allowances. The new types of social pensions were mostly awareded to married women of more than 50 years of age. Pensioning caused by a combination of social and health circumstances was rare. Female applicants were generally awarded lower pensions than male applicants. More than half of the diagnoses included mental diseases, diseases of the musculo-skeletal system and disease of the circulation. In 1985, 15% of the applicants were abusers, mainly of alcohol. 50% of male applicants younger than 50 years of age were abusers. The abusers were very disabled.
Subject(s)
Disability Evaluation , Pensions , Adolescent , Adult , Aged , Alcoholism/epidemiology , Denmark , Female , Humans , Male , Middle Aged , Socioeconomic Factors , Substance-Related Disorders/epidemiologyABSTRACT
A 34-year-old woman with postcoital bleeding due to an extra-medullary solitary plasmocytoma at the uterine cervix is presented. The condition is very rare--only 4 cases have been described in the literature. The patient was treated with conization, and no sign of local recurrence or generalized disease appeared during a 3-year follow-up period.
