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1.
Proc Natl Acad Sci U S A ; 106(5): 1305-12, 2009 Feb 03.
Article in English | MEDLINE | ID: mdl-19179280

ABSTRACT

The Millennium Ecosystem Assessment (MA) introduced a new framework for analyzing social-ecological systems that has had wide influence in the policy and scientific communities. Studies after the MA are taking up new challenges in the basic science needed to assess, project, and manage flows of ecosystem services and effects on human well-being. Yet, our ability to draw general conclusions remains limited by focus on discipline-bound sectors of the full social-ecological system. At the same time, some polices and practices intended to improve ecosystem services and human well-being are based on untested assumptions and sparse information. The people who are affected and those who provide resources are increasingly asking for evidence that interventions improve ecosystem services and human well-being. New research is needed that considers the full ensemble of processes and feedbacks, for a range of biophysical and social systems, to better understand and manage the dynamics of the relationship between humans and the ecosystems on which they rely. Such research will expand the capacity to address fundamental questions about complex social-ecological systems while evaluating assumptions of policies and practices intended to advance human well-being through improved ecosystem services.


Subject(s)
Ecosystem , Environment , Conservation of Natural Resources , Humans , Models, Theoretical , Probability , Species Specificity
2.
Phytother Res ; 22(8): 1013-6, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18618525

ABSTRACT

The antimicrobial activity of the sequential n-hexane, acetone and 50% aqueous methanol extracts of leaves, stem bark and roots of four species of medicinal plants, Cassia sieberiana DC. (Leguminosae), Haematostaphis barteri Hook. f. (Anacardiaceae), Mitragyna inermis (Willd.) O. Kuntze (Rubiaceae) and Pseudocedrela kotschyi (Schweinf.) Harms (Meliaceae), from Ghana were tested against Bacillus subtilis, Pseudomonas syringae and Cladosporium herbarum using TLC direct-autobiographic methods. Extracts from leaves, stem bark and roots of the four species gave a positive result against at least one test organism. Twelve of the 36 extracts were active against B. subtilis, four extracts were active against P. syringae and six were active against C. herbarum. Preliminary chemical analysis revealed the presence of flavonoids, stilbenes and alkaloids. This is the first report of a stilbene from the Anacardiaceae.


Subject(s)
Anti-Infective Agents/pharmacology , Medicine, African Traditional , Plant Extracts/pharmacology , Plants, Medicinal/chemistry , Anti-Infective Agents/chemistry , Bacillus subtilis/drug effects , Cassia/chemistry , Cladosporium/drug effects , Ghana , Meliaceae/chemistry , Microbial Sensitivity Tests , Mitragyna/chemistry , Plant Extracts/chemistry , Pseudomonas syringae/drug effects
4.
J Ethnopharmacol ; 99(2): 273-9, 2005 Jun 03.
Article in English | MEDLINE | ID: mdl-15894138

ABSTRACT

An ethnobotanical study was conducted in the Wechiau Community Hippopotamus Sanctuary area in Ghana, through interviews and quadrate studies, to investigate the range and abundance of species used in the treatment of malaria. Forty-one species belonging to 17 families were encountered during the study. Of the 17 families studied Leguminosae and Anacardiaceae predominated in terms of number of species used to treat malaria. Eight plant species namely, Afraegle paniculata (Rutaceae), Haematostaphis barteri (Anacardiaceae), Indigo era pulchra (Leguminosae), Monanthotaxis sp. (Annonaceae), Ozoroa insignis (Anacardiaceae), Strychnos innocua (Loganiaceae), Strychnos spinosa (Loganiaceae) and Xeroderris stuhlmannii (Leguminosae) have not previously been documented for the treatment of malaria in Ghana. The results are discussed and recommendations made for future research to support the conservation and sustainable harvesting of the species reported to have medicinal properties.


Subject(s)
Antimalarials/pharmacology , Phytotherapy , Plant Extracts/pharmacology , Plants, Medicinal , Antimalarials/administration & dosage , Antimalarials/therapeutic use , Ethnobotany , Ghana , Humans , Medicine, African Traditional , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use
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