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1.
An. pediatr. (2003, Ed. impr.) ; 69(6): 526-532, dic. 2008. ilus, tab
Article in Es | IBECS | ID: ibc-70042

ABSTRACT

Objetivo: Conocer los cambios epidemiológicos y de abordaje diagnóstico y terapéutico de la infección urinaria neonatal en los últimos años. Pacientes y métodos: Estudio descriptivo retrospectivo de las infecciones del tracto urinario (ITU) en pacientes ingresados durante11 años en nuestra unidad neonatal. Se realiza una comparación temporal, por grupo de microorganismos y por resultados en cistouretrografía miccional seriada (CUMS). Resultados: Se estudiaron 106 casos (5 casos por cada 1.000 recién nacidos vivos [RNV]). Los microorganismos más frecuentemente aislados fueron Escherichia coli (81,1 %), Enterococcusfaecalis (6,6 %) y Enterobacter cloacae (4,7 %). La gentamicina tuvo una sensibilidad global del 93,2%, seguida de la cefotaxima con el 91,3 % y de la amoxicilina-ácido clavulánico con el 89,5 %. No encontramos diferencias temporales por microorganismos ni por sensibilidades. Hemos encontrado diferencias en la proteína Creactiva (PCR), en la nitrituria y en la leucocituria en las ITU causadas por E. coli frente a no causadas por este microorganismo, así como en los patrones de sensibilidad antibiótica, ya que las infecciones por microorganismos que no eran E. coli eran más resistentes. No se encontraron diferencias por microorganismos en pacientes con CUMS normal y patológica. Encontramos alteraciones en la ecografía y en la CUMS en el 35,2 y en el 21,4 % de la serie, respectivamente. Conclusiones: La ITU es un problema frecuente en nuestro medio. E. coli es el microorganismo más frecuentemente aislado. En las ITU no causadas por E. coli se produce una mayor resistencia a los tratamientos habituales, aunque en ellas no se detectan más datos patológicos en las pruebas de imagen. No encontramos aumento alguno de resistencias antibióticas a lo largo del estudio (AU)


Objective: To find out the epidemiological and management changes of urinary tract infection over the last years. Patients and methods: Descriptive retrospective review of patients with urinary tract infections (UTIs) admitted to our neonatal unitover an 11 year period. A temporal, microorganism group and voiding cystourethrography (VCUG) group comparison. Results: We studied 106 cases (5 cases/1,000 alive newborns).The most commonly isolated microorganisms were Escherichiacoli (81.1%), Enterococcus faecalis (6.6 %) and Enterobacter cloacae (4.7 %). Gentamicin had an overall sensitivity of 93.2 %, followed by cefotaxime 91.3 % and amoxicillin-clavulanic acid 89.5 %. We did not found temporal differences in microorganisms or sensitivities. We found differences in C reactive protein, nitrate and leucocyte values in E. coli versus non-E. coli UTIs, as well as patterns of antibiotic sensitivity with more resistances by non-E. coli microorganisms. No differences were found in patients with normal and pathological VCUG. We found ultrasound and VCGU disturbances in 35.2% and 21.4%, respectively. Conclusions: UTI is a common problem in our area. The most frequently isolated microorganism is E. coli. Non-E. coli UTI shave more resistances to usual therapies, although these did not show any increase in disease in the imaging tests. We found no increase in resistances throughout the study (AU)


Subject(s)
Humans , Male , Female , Infant, Newborn , Urinary Tract Infections/diagnosis , Urinary Tract Infections/microbiology , Urinary Tract Infections/pathology , Gentamicins , Sensitivity and Specificity , Retrospective Studies , Escherichia coli/isolation & purification , Escherichia coli/pathogenicity , Enterococcus faecalis/isolation & purification , Enterococcus faecalis/pathogenicity , Enterobacter cloacae/isolation & purification , Enterobacter cloacae/pathogenicity , Cefotaxime/therapeutic use , Amoxicillin-Potassium Clavulanate Combination/therapeutic use , Signs and Symptoms
2.
An Pediatr (Barc) ; 69(6): 526-32, 2008 Dec.
Article in Spanish | MEDLINE | ID: mdl-19128765

ABSTRACT

OBJECTIVE: To find out the epidemiological and management changes of urinary tract infection over the last years. PATIENTS AND METHODS: Descriptive retrospective review of patients with urinary tract infections (UTIs) admitted to our neonatal unit over an 11 year period. A temporal, microorganism group and voiding cystourethrography (VCUG) group comparison. RESULTS: We studied 106 cases (5 cases/1,000 alive newborns). The most commonly isolated microorganisms were Escherichia coli (81.1%), Enterococcus faecalis (6.6%) and Enterobacter cloacae (4.7%). Gentamicin had an overall sensitivity of 93.2%, followed by cefotaxime 91.3% and amoxicillin-clavulanic acid 89.5%. We did not found temporal differences in microorganisms or sensitivities. We found differences in C reactive protein, nitrate and leucocyte values in E. coli versus non-E. coli UTIs, as well as patterns of antibiotic sensitivity with more resistances by non-E. coli microorganisms. No differences were found in patients with normal and pathological VCUG. We found ultrasound and VCGU disturbances in 35.2% and 21.4%, respectively. CONCLUSIONS: UTI is a common problem in our area. The most frequently isolated microorganism is E. coli. Non-E. coli UTIs have more resistances to usual therapies, although these did not show any increase in disease in the imaging tests. We found no increase in resistances throughout the study.


Subject(s)
Urinary Tract Infections/microbiology , Female , Humans , Infant, Newborn , Male , Retrospective Studies , Time Factors , Urinary Tract Infections/drug therapy
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