Subject(s)
Pyoderma Gangrenosum , Sweet Syndrome , Vasculitis, Leukocytoclastic, Cutaneous , Humans , Pyoderma Gangrenosum/complications , Pyoderma Gangrenosum/diagnosis , Pyoderma Gangrenosum/drug therapy , Vasculitis, Leukocytoclastic, Cutaneous/complications , Vasculitis, Leukocytoclastic, Cutaneous/diagnosis , Vasculitis, Leukocytoclastic, Cutaneous/drug therapy , ErythemaSubject(s)
Basal Cell Nevus Syndrome/genetics , Germ-Line Mutation/genetics , Receptors, Cell Surface/genetics , Skin Neoplasms/genetics , Adolescent , Adult , Amino Acid Sequence , Asian People/genetics , Basal Cell Nevus Syndrome/ethnology , Basal Cell Nevus Syndrome/pathology , Female , Humans , Japan , Male , Middle Aged , Molecular Sequence Data , Patched Receptors , Patched-1 Receptor , Pedigree , Receptors, Cell Surface/analysis , Skin Neoplasms/ethnology , Skin Neoplasms/pathologyABSTRACT
Cutaneous larva migrans is caused by various nematodes. Skin manifestations may include superficial or creeping eruptions, folliculitis, and migratory subcutaneous nodules. We report a 52-year-old man with asymptomatic, multiple eruptive papules and nodules on the face and neck caused by the larvae of an unknown nematode. The patient never had any creeping or migratory eruptions. Our case is very unusual and differs from previously reported cases of cutaneous larva migrans.
Subject(s)
Larva Migrans/pathology , Nematode Infections/pathology , Facial Dermatoses/pathology , Humans , Male , Middle AgedABSTRACT
Hemophagocytic syndrome is a systemic reactive histiocytic proliferative disorder affecting the reticuloendothelial system. Skin lesions develop in 12.5% to 55.6% of the patients. We report a 35-year-old woman with systemic lupus erythematosus and Graves' disease complicated with parvovirus B19-associated hemophagocytic syndrome. She presented with slightly infiltrated erythematous macules and plaques with ulcers on the scalp, face, and back. A skin biopsy specimen taken from an area of facial erythema demonstrated typical phagocytic cells in the skin. Hemophagocytic syndrome-associated specific cutaneous lesions should be included in the differential diagnosis of facial and nonfacial erythema in patients with systemic lupus erythematosus.
