ABSTRACT
To provide a more realistic method for practicing anterior segment surgery, a device was designed that incorporates aspects of currently available cadaver globe fixation methods. A Styrofoam head was fitted with a funnel and tubing system that allows for direct application of variable external suction to a globe placed in an artificial socket. Prototypes were tested in a wet lab environment, which demonstrated that this method provides reliable globe fixation and allows for variable control of intraocular pressure during a variety of anterior and posterior segment surgical techniques.
Subject(s)
Anterior Eye Segment/surgery , Models, Anatomic , Ophthalmologic Surgical Procedures/instrumentation , Orbit , Suction/instrumentation , Humans , Internship and Residency , Ophthalmologic Surgical Procedures/education , Ophthalmology/education , Teaching/methodsABSTRACT
OBJECTIVE: To highlight the various causes of gaze-evoked amaurosis. DESIGN: Retrospective noncomparative interventional case series. PARTICIPANTS: Five patients treated at our facility over the past 6 years. METHODS: Clinical presentation, radiologic studies, surgical management, and postsurgical results are presented. MAIN OUTCOME MEASURES: Visual acuity, clinical findings of gaze-evoked amaurosis. RESULTS: Only two patients had classic intraorbital etiologies, one with an intraconal cavernous hemangioma and one with an intraconal foreign body. Three patients had extraorbital processes, two with orbital fractures and one with a sinus tumor. Only two of our patients initially were aware of the gaze-evoked amaurosis at presentation. Appropriate surgery was curative in all cases. CONCLUSIONS: Gaze-evoked amaurosis is a rare condition, classically implicating intraconal orbital pathology. In one of the largest case series published to date, we found extraorbital etiologies are also capable of producing gaze-evoked vision loss. Gaze-evoked amaurosis should be suspected and tested for in any orbital condition.
Subject(s)
Blindness/etiology , Eye Movements , Adolescent , Adult , Angiofibroma/complications , Angiofibroma/pathology , Angiofibroma/surgery , Eye Foreign Bodies/complications , Eye Foreign Bodies/pathology , Eye Foreign Bodies/surgery , Female , Hemangioma, Cavernous/complications , Hemangioma, Cavernous/pathology , Hemangioma, Cavernous/surgery , Humans , Male , Maxillary Fractures/complications , Maxillary Fractures/pathology , Maxillary Fractures/surgery , Middle Aged , Nasopharyngeal Neoplasms/complications , Nasopharyngeal Neoplasms/pathology , Nasopharyngeal Neoplasms/surgery , Ocular Motility Disorders/etiology , Orbit/injuries , Orbital Fractures/complications , Orbital Fractures/pathology , Orbital Fractures/surgery , Orbital Neoplasms/complications , Orbital Neoplasms/pathology , Orbital Neoplasms/surgery , Retrospective Studies , Tomography, X-Ray Computed , Zygomatic Fractures/complications , Zygomatic Fractures/pathology , Zygomatic Fractures/surgeryABSTRACT
Adequate anterior segment visualization during cataract surgery can be hindered when excessive tear film secretions precipitate on the corneal surface before the initial corneal incision is made. In most cases, room-temperature balanced salt solution applied to the corneal surface clears the debris. However, in cases in which tear film precipitates persist after the use of room-temperature balanced salt solution, the application of warm balanced salt solution can provide rapid and sustained dispersion of the precipitates. We present our experience using this technique.
Subject(s)
Cataract Extraction/methods , Ophthalmic Solutions/therapeutic use , Sodium Chloride/therapeutic use , Tears/chemistry , Adult , Body Temperature , Chemical Precipitation , Cornea/physiopathology , Female , Hot Temperature , Humans , Intraoperative Period , Male , Reference ValuesABSTRACT
In addition to the previously reported bioactive kahalalide F six new peptides are described. Six of these, including kahalalide F, are cyclic depsipeptides, ranging from a C(31) tripeptide to a C(75) tridecapeptide isolated from a sacoglossan mollusk, Elysiarufescens. The mollusk feeds on a green alga, Bryopsis sp., which has also been shown to elaborate some of these peptides in smaller yields, in addition to an acyclic analog of F, kahalalide G. The bioassay results of antitumor, antiviral, antimalarial, and OI (activity against AIDS opportunistic infections) tests are reported.
