1.
RSC Adv
; 10(13): 7698-7707, 2020 Feb 18.
Article
in English
| MEDLINE
| ID: mdl-35492186
ABSTRACT
A Cu-based homogeneous catalytic system was proposed for the preparation of imides from alkene-tethered amides. Here, O2 acted as a terminal oxidant and a cheap and easily available oxygen source. The cleavage of C[double bond, length as m-dash]C bonds and the formation of C-N bonds were catalyzed by Cu(ii) salts with proper nitrogen-containing ligands under 100 °C. The synthesis approach has potential applications in pharmaceutical syntheses. Moreover, scaled-up experiments confirmed the practical applicability.