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1.
Article in French | AIM (Africa) | ID: biblio-1271854

ABSTRACT

La maladie de Ménétrier est une affection précancéreuse de l'estomac. Très peu d'études ont concerné cette affection dans le monde. Nous rapportons 3 cas colligés au Centre Hospitalier Universitaire Yalgado Ouédraogo. L'âge de nos malades était compris entre 51 et 73 ans avec une moyenne de 59 ans. Il s'agissait de 2 hommes et une femme de niveau socio-économique bas. Le tableau clinique était dominé par les épigastralgies, les hémorragies digestives hautes et les vomissements. La fibroscopie digestive montrait une gastropathie hypertrophique chez les trois patients avec suspicion de dégénérescence chez deux d'entre eux. L'histologie était en faveur de la maladie de Ménétrier dans tous les cas; mais elle ne confirmait la dégénérescence que chez un patient. Deux de nos patients ont bénéficié d'un traitement médical à base d'oméprazole, d'amoxicilline et de métronidazole chez l'un, clarithromycine chez l'autre. La troisième patiente a bénéficié d'une gastrectomie totale. Les suites opératoires ont été simples. La patiente s'est alimentée à base de produits liquides puis semi liquides. Les deux autres ont été perdus de vue. Ainsi, la maladie de Ménétrier reste rare et des études multicentriques pourraient permettre de dégager des protocoles de prise en charge adaptés à notre pays


Subject(s)
Burkina Faso , Case Reports , Gastrectomy , Gastritis, Hypertrophic/diagnosis , Gastritis, Hypertrophic/drug therapy , Gastritis, Hypertrophic/surgery
2.
Bull Cancer ; 105(12): 1119-1125, 2018 Dec.
Article in French | MEDLINE | ID: mdl-30392708

ABSTRACT

OBJECTIVE: To study the epidemiology and histology of primary digestive cancers in semi-urban areas in Burkina Faso. METHODS: This was a descriptive study over 5 years conducted simultaneously in 2 regional hospitals in Burkina Faso. It included all patients treated for primary digestive cancers. RESULTS: A total of 352 were included. The average age of the patients was 44.3 years. Patients aged between 30 and 49 years accounted for 44.6%. There were 175 male patients (49.7%). In the patient's history, we found 6 cases of ulcerative colitis, 2 cases of colonic adenoma, and 5 cases of hepatic cirrhosis. The average consultation time was 138 days. In 70 cases (19.9%), the cancer was discovered at a stage of complication. The most affected organs were the colon and rectum (36.7%), the stomach (21.9%) and the pancreas (19.0%). The most common histological type of cancer was adenocarcinoma (67.6%). One hundred and forty-four patients (40.9%) were diagnosed at stage 3 and 65 others (18.5%) at stage 4 of TMN staging. Therapeutically, surgery was used in 307 patients (87.2%) and chemotherapy in 63 cases (17.9%). The one-year mortality rate was 29%. CONCLUSION: In Burkina Faso rural area, primary digestive cancers occur in young patients with no predominance of sex. Colorectal cancer remains the most common.


Subject(s)
Gastrointestinal Neoplasms , Adenocarcinoma/epidemiology , Adenocarcinoma/pathology , Adenocarcinoma/therapy , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Burkina Faso/epidemiology , Child , Child, Preschool , Colonic Neoplasms/epidemiology , Colonic Neoplasms/pathology , Colonic Neoplasms/therapy , Delayed Diagnosis , Female , Gastrointestinal Neoplasms/epidemiology , Gastrointestinal Neoplasms/pathology , Gastrointestinal Neoplasms/therapy , Humans , Male , Middle Aged , Pancreatic Neoplasms/epidemiology , Pancreatic Neoplasms/pathology , Pancreatic Neoplasms/therapy , Rectal Neoplasms/epidemiology , Rectal Neoplasms/pathology , Rectal Neoplasms/therapy , Sex Distribution , Stomach Neoplasms/epidemiology , Stomach Neoplasms/pathology , Stomach Neoplasms/therapy , Young Adult
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