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2.
BJR Open ; 6(1): tzae007, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38544877

ABSTRACT

Recent advances in percutaneous image-guided techniques have empowered interventional radiologists with diverse treatment options for the management of musculoskeletal lesions. Of note, there is growing utility for cementoplasty procedures, with indications ranging from stabilization of bone metastases to treatment of painful vertebral compression fractures. Likewise, cryoablation has emerged as a viable adjunct in the treatment of both primary and secondary bone and soft tissue neoplasms. These treatment options have been progressively incorporated into the multidisciplinary approach to holistic care of patients, alongside conventional radiotherapy, systemic therapy, surgery, and analgesia. This review article serves to outline the indications, technical considerations, latest developments, and evidence for the burgeoning role of cementoplasty and cryoablation in the musculoskeletal system, with an emphasis on pain palliation and tumour control.

3.
Br J Radiol ; 97(1156): 705-715, 2024 Mar 28.
Article in English | MEDLINE | ID: mdl-38291893

ABSTRACT

Dual-energy CT (DECT) is an exciting application in CT technology conferring many advantages over conventional single-energy CT at no additional with comparable radiation dose to the patient. Various emerging and increasingly established clinical DECT applications in musculoskeletal (MSK) imaging such as bone marrow oedema detection, metal artefact reduction, monosodium urate analysis, and collagen analysis for ligamentous, meniscal, and disc injuries are made possible through its advanced DECT post-processing capabilities. These provide superior information on tissue composition, artefact reduction and image optimization. Newer DECT applications to evaluate fat fraction for sarcopenia, Rho/Z application for soft tissue calcification differentiation, 3D rendering, and AI integration are being assessed for future use. In this article, we will discuss the established and developing applications of DECT in the setting of MSK radiology as well as the basic principles of DECT which facilitate them.


Subject(s)
Bone Marrow Diseases , Musculoskeletal Diseases , Radiography, Dual-Energy Scanned Projection , Humans , Tomography, X-Ray Computed/methods , Radiography, Dual-Energy Scanned Projection/methods , Musculoskeletal Diseases/diagnostic imaging , Uric Acid
4.
Cardiovasc Intervent Radiol ; 46(11): 1504-1516, 2023 Nov.
Article in English | MEDLINE | ID: mdl-37783774

ABSTRACT

Musculoskeletal tissues are often subjected to deleterious effects stemming from traumatic injuries or degenerative pathologies, which can impede the body's natural repair response. The advent of regenerative medicine has emerged as a promising therapeutic approach in modern patient care. Among the interventions in this cutting-edge field, platelet-rich plasma (PRP) and cell-based therapies, such as mesenchymal stem cells, have garnered significant attention. In this article, we endeavor to provide an overview of the current practices and recent developments in PRP therapy, with a particular emphasis on the clinical applications for musculoskeletal pathologies.


Subject(s)
Platelet-Rich Plasma , Humans
5.
Skeletal Radiol ; 52(8): 1599-1604, 2023 Aug.
Article in English | MEDLINE | ID: mdl-36562821

ABSTRACT

We describe a case of chronic tophaceous gout affecting the spine, hands, elbows, feet, and knees in a 67-year-old man with serum urate levels at 549 µmol/L whose response to treatment was successfully mapped using dual-energy computed tomography (DECT). The patient presented with exacerbation of acute-on-chronic lumbar back pain. He had received a diagnosis of gout 3 years prior to this presentation yet was not on any urate-lowering therapy. The patient received febuxostat 80 mg and colchicine 0.3 mg once daily and underwent DECT to assess baseline monosodium urate (MSU) burden. At baseline, MSU deposits were seen in the hands, elbows, feet, knees, and lumbar spine including the left L5-S1 facet joint encroaching onto the neural foramen. After 2.5 years of treatment, serum urate level was within the target range (< 360 µmol/L), and the patient underwent a follow-up DECT that revealed almost full resolution of MSU deposition in the spine, including the MSU-burdened facet joint and neural foramen in the lumbar spine, in addition to all the affected peripheral joints. This case is the first report of radiological evidence of nearly complete resolution of MSU deposits in spinal gout on DECT after urate-lowering therapy treatment, which demonstrates the utility of this imaging modality as a non-invasive investigational point-of-care imaging modality for mapping treatment response and identifying the etiology of back pain in a patient with chronic tophaceous spinal gout.


Subject(s)
Gout , Uric Acid , Male , Humans , Aged , Point-of-Care Systems , Gout/diagnostic imaging , Gout/drug therapy , Febuxostat , Tomography, X-Ray Computed/methods
6.
Semin Musculoskelet Radiol ; 26(5): 527-534, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36535588

ABSTRACT

Radiologic knowledge of different fracture patterns involving the shoulder girdle is an important tool to generate clinically relevant reports, identify concomitant injuries, guide management decisions, and predict and minimize complications, such as nonunion, osteoarthritis, osteonecrosis, and hardware failure. Complex unstable injuries like scapulothoracic dissociation can also occur because of shoulder girdle trauma. Management options may vary from conservative to surgical, depending on the fracture type and patient factors. Injuries around the shoulder girdle can involve the glenohumeral articulation, scapula, superior shoulder suspensory complex, acromioclavicular joints, and scapulothoracic articulation.


Subject(s)
Acromioclavicular Joint , Shoulder Injuries , Shoulder Joint , Humans , Acromioclavicular Joint/injuries , Scapula/injuries , Shoulder
7.
Tech Vasc Interv Radiol ; 25(1): 100800, 2022 Mar.
Article in English | MEDLINE | ID: mdl-35248324

ABSTRACT

Image guided percutaneous biopsy has become the initial procedure of choice in most cases for obtaining bone samples for histological and microbiological assessment. It is a minimally invasive procedure which offers multiple advantages over open surgical biopsy including maintenance of bone structure, minimal soft tissue injury, reduced need of general anesthesia, reduced hospital stay and a low rate of post-procedure complications. In some cases, it can be combined with therapeutic procedures such as cementoplasty and cryoablation via the same access route. For the radiologist, knowledge of the key principles is essential for a safe and effective procedure, particularly when a sarcoma of bone is in the differential diagnosis. In this article we cover the core concepts of percutaneous bone biopsy including indications and contraindications, essential planning steps, appropriate imaging modalities, equipment selection, common approaches, technique as well as avoiding, recognizing and treating complications. Recent technological advancements in this field are also discussed.


Subject(s)
Bone Neoplasms , Cryosurgery , Soft Tissue Neoplasms , Biopsy , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/surgery , Cryosurgery/adverse effects , Humans , Image-Guided Biopsy/adverse effects , Image-Guided Biopsy/methods , Radiologists , Soft Tissue Neoplasms/diagnostic imaging , Soft Tissue Neoplasms/surgery
8.
Semin Musculoskelet Radiol ; 26(1): 3-12, 2022 Feb.
Article in English | MEDLINE | ID: mdl-35139555

ABSTRACT

Ice hockey is a fast-paced contact sport with a high incidence of injuries. Upper extremity injury is one of the most common regions of the body to be injured in hockey. This imaging review will equip the radiologist with a knowledge of the more common and severe upper extremity injuries that occur in this sport.


Subject(s)
Arm Injuries , Athletic Injuries , Hockey , Arm Injuries/diagnostic imaging , Athletic Injuries/diagnostic imaging , Diagnostic Imaging , Humans , Incidence , Upper Extremity/diagnostic imaging , Upper Extremity/injuries
9.
Semin Musculoskelet Radiol ; 26(1): 1-2, 2022 Feb.
Article in English | MEDLINE | ID: mdl-35139554

Subject(s)
Sports , Humans
10.
Semin Musculoskelet Radiol ; 26(1): 13-27, 2022 Feb.
Article in English | MEDLINE | ID: mdl-35139556

ABSTRACT

Hockey is a fast-paced contact sport with a high incidence of injuries. Although injuries are more frequent among elite players, recreational hockey injuries are a common issue faced by primary care and emergency physicians. Lower extremity injuries in hockey are particularly important because they account for approximately a third of all injuries and > 60% of all overuse injuries. This pictorial review provides the general and specialty trained radiologist with a knowledge of the patterns of lower extremity injury that occur in ice hockey.


Subject(s)
Athletic Injuries , Hockey , Leg Injuries , Athletic Injuries/diagnostic imaging , Humans , Incidence , Leg Injuries/diagnostic imaging , Lower Extremity/diagnostic imaging
11.
Semin Musculoskelet Radiol ; 26(1): 28-40, 2022 Feb.
Article in English | MEDLINE | ID: mdl-35139557

ABSTRACT

Hockey is a demanding contact sport with growing popularity around the world. This article is part of a review series in this issue of Seminars in Musculoskeletal Radiology that summarizes epidemiological research on the patterns of ice hockey injuries as well as provides pictorial examples for a radiologist's perspective. We focus on non-extremity pathologies which encompass many of the most devastating injuries of hockey, namely those involving the head, neck, face, spine, and body.


Subject(s)
Athletic Injuries , Brain Concussion , Craniocerebral Trauma , Hockey , Athletic Injuries/diagnostic imaging , Craniocerebral Trauma/diagnostic imaging , Diagnostic Imaging , Humans
12.
Can Assoc Radiol J ; 73(3): 549-556, 2022 Aug.
Article in English | MEDLINE | ID: mdl-35006011

ABSTRACT

Purpose: To determine the sensitivity and specificity of dual-energy CT (DECT) virtual noncalcium images (VNCa) with bone and soft tissue reconstructions in the diagnosis of osteomyelitis. Materials & Methods: Between December 1, 2014 to December 1, 2020, 91 patients who had 99 DECT performed for a clinical indication of osteomyelitis with corresponding MRI, triphasic bone scan and/or white blood cell scintigraphy with CT/SPECT performed either 2 weeks before or 1 month after the DECT were retrospectively identified. The presence or absence of osteomyelitis was established using a second imaging test, bone biopsy or surgery. Two radiologists interpreted VNCa images alone and with bone and soft tissue reconstructions for osteomyelitis. Fleiss k statistics was used to assess inter-level agreement. Results: Osteomyelitis was present in 26 cases (26.2%), of which 4 cases (4%) had co-existing septic arthritis. DECT was performed at the following sites: ankle/foot (n = 59), calf (n = 12), knee (n = 3), thigh (n = 7), hip (n = 9), pelvis (n = 6), wrist/hand (n = 1), and shoulder (n = 2). Sensitivity with VNCa images alone was 53.8% and 73.1% and specificity was 84.9% and 71.2%. Sensitivity with VNCa images and bone and soft tissue reconstructions was 80.8% and 80.8% and specificity was 80.8% and 72.6%. Interobserver agreement was 76.7% (76 of 99 cases), for VNCa images alone (k = .487), and 66.7% (66 of 99 patients) for bone and soft tissue reconstructions with VNCa images together (k = .390). Conclusion: When VNCa images were combined with bone and soft tissue reconstructions, there is improved sensitivity in the diagnosis of osteomyelitis.


Subject(s)
Bone Marrow Diseases , Edema , Osteomyelitis , Bone Marrow/pathology , Bone Marrow Diseases/pathology , Edema/pathology , Humans , Magnetic Resonance Imaging/methods , Osteomyelitis/diagnostic imaging , Osteomyelitis/pathology , Retrospective Studies , Sensitivity and Specificity , Tomography, X-Ray Computed/methods
13.
Skeletal Radiol ; 51(3): 681-685, 2022 Mar.
Article in English | MEDLINE | ID: mdl-34554278

ABSTRACT

A nuchal-type fibroma is a rare, benign fibrous tumour that typically occurs in the posterior neck along the midline, but can occur in extra-nuchal locations, most commonly in the back, shoulder and face. We present a biopsy-proven case that arose as a result of heavy gym-related activities. In particular, a heavy barbell was rested on his vertebral prominence at the level of C7/T1 during leg squatting. Repetitive trauma as a cause for extra-nuchal-type fibromas has been sparsely reported, but we suggest that sustained high pressure is an additional required feature. Although this lesion was in the posterior neck, it was contained entirely within the subcutaneous tissues without involvement of the nuchal ligament. Hence, it was considered an extra-nuchal fibroma. A description of key ultrasound and MRI imaging characteristics are provided to assist in making the diagnosis, along with a review of the current literature and a discussion of differential diagnoses.


Subject(s)
Fibroma , Head and Neck Neoplasms , Skin Neoplasms , Soft Tissue Neoplasms , Fibroma/diagnostic imaging , Humans , Neck
14.
PLoS One ; 16(12): e0261657, 2021.
Article in English | MEDLINE | ID: mdl-34941915

ABSTRACT

INTRODUCTION: Desmoid tumor is a locally-invasive neoplasm that causes significant morbidity. There is recent interest in cryotherapy for treatment of extra-abdominal desmoid tumors. This systematic review assesses evidence on safety and efficacy of cryotherapy in the treatment of extra-abdominal desmoid tumors. MATERIALS AND METHODS: The systematic review was conducted with reference to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Literature search was performed using MEDLINE and the Cochrane Central Register of Controlled Trials. 9 full text papers were reviewed and meta-analysis was performed for measures of safety, efficacy and symptom relief. RESULTS: The estimated pooled proportion of major and minor complications was 4.2% (95% CI, 1.8-9.6; I 2 = 0%) and 10.2% (95% CI, 5.7-17.8; I 2 = 0%) respectively. The estimated pooled proportion of non-progressive disease rate of all studies was 85.8% (95% CI, 73.4-93.0; I 2 = 32.9%). The estimated progression free survival rate at 1 year was 84.5% (95% CI:74.6-95.8) and 78.0% at 3 years (95% CI: 63.8-95.3). As for pain control, the estimated pooled proportion of patients with decrease in visual analogue scale (VAS) > = 3 for those with VAS > = 3 before treatment for 2 studies was 87.5% (95% CI, 0.06-100; I 2 = 71.5%) while 37.5% to 96.9% of patients were reported to have experienced partial or complete symptom relief in the other studies. CONCLUSION: Cryotherapy is a safe and effective treatment modality for extra-abdominal desmoid tumors with efficacy similar to those treated with traditional strategies in the short to medium term.


Subject(s)
Cryotherapy/methods , Fibromatosis, Aggressive/therapy , Cryotherapy/adverse effects , Fibromatosis, Aggressive/epidemiology , Humans , Progression-Free Survival , Treatment Outcome
15.
J Vasc Interv Radiol ; 32(9): 1277-1287, 2021 09.
Article in English | MEDLINE | ID: mdl-34089889

ABSTRACT

PURPOSE: To determine the efficacy and safety of cryoablation in patients with desmoid tumors (DTs) retrospectively over a 10-year period at a single institution. MATERIALS AND METHODS: Between February 25, 2010, and February 25, 2020, 25 patients (age, 12-80 years) with 26 lesions (mean preprocedural tumor volume was 237 cm3) were treated over 44 cryoablation procedures. Eleven patients were treated with first-line therapy. Fourteen patients had previous medical therapy, radiotherapy, and/or surgery. Subsequent clinical follow-up, imaging outcomes, and safety were analyzed for technical success, change in total lesion volume (TLV) and viable tumor volume (VTV), modified response evaluation criteria in solid tumors (mRECIST), progression-free survival (PFS) for tumor progression and symptom recurrence, symptom improvement, and procedure-related complications. Symptomatic improvement was defined as documentation of relief of pain (partial or complete) and/or functional impairment. RESULTS: All procedures were technically successful. At 7-12 months, median changes in TLV and VTV were -6.7% (P = .809) and -43.7% (P = .01), respectively. At 10-12 months, the mRECIST responses were complete response, 0%; partial response, 61.5% (8/13); stable disease, 30.8% (4/13); and progressive disease, 7.7% (1/13). The median PFS for tumor progression and symptom recurrence were not reached, with a median follow-up of 15.3 and 21.0 months, respectively. Symptomatic relief (partial or complete) was achieved in 96.9% (32/33) of patients. One major complication was noted (2.4%). CONCLUSIONS: In this retrospectively identified cohort, cryoablation was effective and safe for the local control of extra-abdominal DTs in short-term follow-up.


Subject(s)
Cryosurgery , Fibromatosis, Aggressive , Adolescent , Adult , Aged , Aged, 80 and over , Child , Cryosurgery/adverse effects , Fibromatosis, Aggressive/diagnostic imaging , Fibromatosis, Aggressive/surgery , Humans , Middle Aged , Progression-Free Survival , Retrospective Studies , Treatment Outcome , Young Adult
16.
Can Assoc Radiol J ; 72(3): 548-556, 2021 Aug.
Article in English | MEDLINE | ID: mdl-32103671

ABSTRACT

OBJECTIVE: To study the impact of 24/7/365 attending radiologist coverage on the turnaround time (TAT) of trauma and nontrauma cases in an emergency and trauma radiology department. PATIENTS AND METHODS: This was a retrospective chart review in which TAT of patients coming to the emergency department between 2 periods: (1) December 1, 2012, to September 30, 2013, and (2) January 1, 2017, to January 30, 2018, and whose reports were read by an attending emergency and trauma radiologist was noted. RESULTS: The 24/7/365 radiology coverage was associated with a significant reduction in TAT of computed tomography reports, and the time reduction was comparable between trauma and nontrauma cases. In adjusted models, the extension of radiology coverage was associated with an average of 7.83 hours reduction in overall TAT (95% confidence interval [CI]: 7.44-8.22) for reports related to trauma, in which 2.73 hours were due to reduction in completion to transcription time (TC; 95% CI: 2.53-2.93), and 5.10 hours were due to reduction in transcription to finalization time (TF; 95% CI: 4.75-5.44). For reports related to nontrauma cases, 24/7/365 coverage was associated with an average of 6.07 hours reduction in overall TAT (95% CI: 3.54-8.59), 2.91 hours reduction in TC (95% CI: 1.55-4.26), and 3.16 hours reduction in TF (95% CI: 0.90-5.42). CONCLUSION: Our pilot study demonstrates that the implementation of on-site 24/7/365 attending emergency radiology coverage at a tertiary care center was associated with a reduced TAT for trauma and nontrauma patients imaging studies. Although the magnitude and precision of estimates were slightly higher for trauma cases as compared to nontrauma cases. Trauma examinations stand to benefit the most from 24/7/365 attending level radiology coverage.


Subject(s)
Emergency Service, Hospital/organization & administration , Radiologists/organization & administration , Radiology Department, Hospital/organization & administration , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Personnel Staffing and Scheduling , Pilot Projects , Retrospective Studies , Tertiary Care Centers/organization & administration , Time Factors , Tomography, X-Ray Computed , Wounds and Injuries/diagnostic imaging
17.
Can Assoc Radiol J ; 72(4): 862-870, 2021 Nov.
Article in English | MEDLINE | ID: mdl-32157902

ABSTRACT

OBJECTIVE: To offer an evidence-based account of the effect of 24/7/365 attending radiologist coverage on the turnaround time (TAT) of trauma-related radiographs finalized within 48 hours of exam completion, drawing data from an emergency radiology department of a tertiary care hospital in Vancouver, British Columbia. MATERIALS AND METHODS: This was a retrospective chart review, where TATs of imaging studies for a sample of trauma patients, who had visited the emergency department of the Vancouver General Hospital between two time periods, January 1 to September 30, 2013, and January 1 to September 30, 2017, were noted. RESULTS: In models adjusted for patient's age, sex, and seasonality, the 24/7/365 attending radiologist coverage was associated with an average of 19.1 (95% confidence interval [CI]: 18.7-19.4) hours of reduction in time from exam completion to report finalization by an attending radiologist. Approximately 11.3 (95% CI: 18.7-19.4) hours was due to reduction in time from exam completion to preliminary diagnosis of reports. When the impact of the increased number of radiology staff in 2017 was removed in the analysis, the overall TAT was reduced by 13.3 (95% CI: 13.0-13.6) hours and the time from exam completion to preliminary report was reduced by 7.8 (95% CI: 7.6-8.1) hours. LIMITATION: Since we have used a simple random sample (SRS) for this research, this study does not describe the burden of reports that are finalized in the emergency and trauma radiology department during the given time periods. CONCLUSION: Our pilot study demonstrates that the implementation of 24/7/365 attending radiology coverage significantly reduces TAT for finalized radiology reports of all modalities of trauma imaging studies in an emergency and trauma radiology department. POLICY IMPLICATION: This research serves the contemporary health-care administration, policymaking information needs by providing the evidence for significantly reduced TAT of finalized radiology reports from a Canadian perspective.


Subject(s)
Diagnostic Imaging/statistics & numerical data , Personnel Staffing and Scheduling/statistics & numerical data , Radiologists/statistics & numerical data , Radiology Department, Hospital/statistics & numerical data , Workflow , Wounds and Injuries/diagnostic imaging , British Columbia , Emergencies , Emergency Service, Hospital , Female , Humans , Male , Middle Aged , Pilot Projects , Retrospective Studies , Tertiary Care Centers , Time Factors
18.
Ann Acad Med Singap ; 49(11): 931-933, 2020 Nov.
Article in English | MEDLINE | ID: mdl-33381793

Subject(s)
Gout , Gout/diagnosis , Humans
19.
Br J Radiol ; 93(1106): 20190620, 2020 Feb 01.
Article in English | MEDLINE | ID: mdl-31573325

ABSTRACT

CT is a readily available imaging modality for cross-sectional characterization of acute musculoskeletal injuries in trauma. Dual-energy CT provides several additional benefits over conventional CT, namely assessment for bone marrow edema, metal artifact reduction, and enhanced assessment of ligamentous injuries. Winter sports such as skiing, snowboarding, and skating can result in high speed and high energy injury mechanisms; dual-energy CT is well suited for the characterization of those injuries.


Subject(s)
Snow Sports/injuries , Tomography, X-Ray Computed/methods , Adult , Ankle Injuries/diagnostic imaging , Bone Marrow Diseases/diagnostic imaging , Edema/diagnostic imaging , Elbow Joint/diagnostic imaging , Female , Femoral Fractures/diagnostic imaging , Hip Injuries/diagnostic imaging , Humans , Imaging, Three-Dimensional , Knee Injuries/diagnostic imaging , Male , Middle Aged , Radius Fractures/diagnostic imaging , Tibial Fractures/diagnostic imaging , Wrist Injuries/diagnostic imaging , Young Adult , Elbow Injuries
20.
Semin Musculoskelet Radiol ; 23(4): 392-404, 2019 Aug.
Article in English | MEDLINE | ID: mdl-31509867

ABSTRACT

Dual-energy computed tomography (DECT) has the potential to detect musculoskeletal pathology with greater sensitivity than conventional CT alone at no additional radiation dose to the patient. It therefore has the potential to reduce the need for further diagnostic imaging or procedures (e.g., joint aspirations in the case of gout or magnetic resonance imaging to confirm undisplaced fractures).DECT is a well-established technique for the detection of gout arthropathy. Multiple newer applications have shown clinical potential including bone marrow edema detection and metal artifact reduction. Collagen analysis, bone marrow lesion detection, and iodine mapping in CT arthrography are areas of possible future application and development.This article outlines 10 tips on the use of DECT imaging of the musculoskeletal system, explaining the technique and indications with practical suggestions to help guide the radiologist.


Subject(s)
Musculoskeletal Diseases/diagnostic imaging , Radiography, Dual-Energy Scanned Projection/methods , Tomography, X-Ray Computed/methods , Musculoskeletal System/diagnostic imaging
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