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1.
Comput Biol Med ; 175: 108523, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38701591

ABSTRACT

Diabetic retinopathy is considered one of the most common diseases that can lead to blindness in the working age, and the chance of developing it increases as long as a person suffers from diabetes. Protecting the sight of the patient or decelerating the evolution of this disease depends on its early detection as well as identifying the exact levels of this pathology, which is done manually by ophthalmologists. This manual process is very consuming in terms of the time and experience of an expert ophthalmologist, which makes developing an automated method to aid in the diagnosis of diabetic retinopathy an essential and urgent need. In this paper, we aim to propose a new hybrid deep learning method based on a fine-tuning vision transformer and a modified capsule network for automatic diabetic retinopathy severity level prediction. The proposed approach consists of a new range of computer vision operations, including the power law transformation technique and the contrast-limiting adaptive histogram equalization technique in the preprocessing step. While the classification step builds up on a fine-tuning vision transformer, a modified capsule network, and a classification model combined with a classification model, The effectiveness of our approach was evaluated using four datasets, including the APTOS, Messidor-2, DDR, and EyePACS datasets, for the task of severity levels of diabetic retinopathy. We have attained excellent test accuracy scores on the four datasets, respectively: 88.18%, 87.78%, 80.36%, and 78.64%. Comparing our results with the state-of-the-art, we reached a better performance.


Subject(s)
Deep Learning , Diabetic Retinopathy , Diabetic Retinopathy/diagnostic imaging , Humans , Neural Networks, Computer , Databases, Factual , Image Interpretation, Computer-Assisted/methods , Algorithms
2.
J Digit Imaging ; 36(4): 1739-1751, 2023 08.
Article in English | MEDLINE | ID: mdl-36973632

ABSTRACT

Diabetic retinopathy (DR) is one of the most common consequences of diabetes. It affects the retina, causing blood vessel damage which can lead to loss of vision. Saving patients from losing their sight or at least slowing the progress of this disease depends mainly on the early detection of this pathology, on top of the detection of its specific stage. Furthermore, the early detection of diabetic retinopathy and the follow-up of the patient's condition remains an arduous task, whether for an experienced expert ophthalmologist or a computer-aided diagnosis technician. In this paper, we aim to propose a new automatic diabetic retinopathy severity level detection method. The proposed approach merges the pyramid hierarchy of the discrete wavelet transform of the retina fundus image with the modified capsule network and the modified inception block proposed, in addition to a new deep hybrid model that concatenates the inception block with capsule networks. The performance of our proposed approach has been validated on the APTOS dataset, as it achieved a high training accuracy of 97.71% and a high testing accuracy score of 86.54%, which is considered one of the best scores achieved in this field using the same dataset.


Subject(s)
Diabetes Mellitus , Diabetic Retinopathy , Humans , Diabetic Retinopathy/diagnostic imaging , Algorithms , Retina , Fundus Oculi , Diagnosis, Computer-Assisted , Diabetes Mellitus/pathology
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