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Presse Med ; 24(12): 577-9, 1995 Mar 25.
Article in French | MEDLINE | ID: mdl-7770404

ABSTRACT

A 32-year old man treated for several years with phenothiazine for chronic psychosis developed acute necrotizing colitis. The causal relationship with neuroleptics was reinforced by the absence of any other treatment and by histological findings including extensive mucosal necrosis without stenotic lesion and without mesenteric vessels alteration. The patient required emergency total colectomy and was discharged after 7 weeks of hospitalisation in the intensive care unit.


Subject(s)
Antipsychotic Agents/adverse effects , Enterocolitis, Pseudomembranous/chemically induced , Acute Disease , Adult , Antipsychotic Agents/therapeutic use , Dose-Response Relationship, Drug , Enterocolitis, Pseudomembranous/pathology , Enterocolitis, Pseudomembranous/surgery , Humans , Male , Phenothiazines , Psychotic Disorders/drug therapy , Time Factors
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