ABSTRACT
PURPOSE: To study the effect of magnetic therapy on the formation of distraction regenerate of the lower jaw in patients with lower micrognathia. MATERIALS AND METHODS: The study comprised 159 patients with inferior micrognathia of congenital and acquired etiology. The patients were divided into 2 groups. The main group consisted of 112 patients who received magnetic therapy: 55 patients with congenital micrognathia and 57 patients with acquired micrognathia. The control group included 47 patients who did not undergo magnetic therapy: 20 patients with congenital micrognathia and 27 patients with acquired micrognathia. Magnetic therapy was performed daily starting from day 1 or 2 after surgery. Ultrasound monitoring began on the 7th day of distraction and was carried out every 3-4 days, which made it possible to assess the dynamics of the formation of the distraction regenerate. RESULTS: Ultrasound examination on the 7th day of distraction revealed that in the main group the number of distraction regenerates of the normotrophic type was 36.5%, hypotrophic type 18%, hypertrophic type 54.5%. In the control group, the corresponding rates were 53%, 31% and 22%. CONCLUSION: Magnetic therapy induces osteogenesis and accelerates the maturation of the distraction regenerate. This makes it possible to accelerate the pace of distraction without reducing the quality of the regenerate.
Subject(s)
Magnetic Field Therapy , Micrognathism , Osteogenesis, Distraction , Humans , Osteogenesis, Distraction/methods , Male , Child , Female , Micrognathism/surgery , Magnetic Field Therapy/methods , Child, Preschool , Mandible/surgery , Treatment OutcomeABSTRACT
An experimental study was made on the removed tonsil to validate clinical efficiency of intralacunar impact of surgical laser beam. The experiment was based on computed tomography of the removed tonsil with intralacunar introduction of the contrast medium before and after intralacunar impact of surgical laser beam. The study demonstrates changes in the lacunar apparatus of the palatine tonsils in response to laser beam radiation. Dilation of the lacunae, disappearance of lacunar narrowings and branches promoted improvement of the drainage function of the lacunar complex of the palatine tonsils.
Subject(s)
Laser Coagulation , Laser Therapy , Palatine Tonsil/surgery , Chronic Disease , Humans , Palatine Tonsil/diagnostic imaging , Radiography , Therapies, Investigational , Tonsillitis/surgerySubject(s)
Laser Therapy , Tonsillitis/surgery , Adolescent , Adult , Aged , Child , Chronic Disease , Humans , Middle Aged , Retrospective Studies , TonsillectomyABSTRACT
A mathematical model of the glycolytic system with the cytoplasmic coenzymes NAD+ and NADH as essential variables is proposed. It has been shown that any increase in the steady-state concentration of NADH will reduce the range of activity of the "generalized" ATPase, wherein the level of ATP is stabilized. Such a reduction in the range of ATP stabilization may be caused by an increasing rate of the pyruvate loss into non-glycolytic pathways, in particular, into mitochondria. This effect may be compensated by increasing oxidation of NADH by the dehydrogenases of H+-transferring cytosol-mitochondrial shuttles (malate-aspartate or alpha-glycerophosphate). The properties of the complete model were compared with those of its simplified version, which takes account only of the phosphotransferase reactions of glycolysis. The effects of various factors, which do not alter the level of NADH in the system, may be studied within the scope of the simplified model.
