The effect of orthodontic tooth movement on the sensitivity of dental pulp: A systematic review and meta-analysis.

Objectives: Orthodontic tooth movement (OTM) is a process that's initiated by orthodontic forces. As a consequence, the forces could restrict pulpal blood supply, possibly affecting dental pulp. The study aimed to review the available evidence on the short and long-term effects of orthodontic tooth movement on dental pulp sensitivity and to identify clinically relevant risk factors. Sources: PubMed, Embase, Scopus, and Web of Science were searched for papers from 1990 to the end of December 2021. Study selection: The studies that evaluated dental pulp sensitivity of teeth undergoing OTM were included in the systematic review. Randomized, nonrandomized and case-controlled studies were included in the analysis. Risk of bias in each study was assessed using the ROBINS-I tool. Data: The systematic search yielded an initial sample of 1110 studies, 17 were included in qualitative analysis. Most studies were classified as moderate risk of bias, however only limited long-term evidence with a higher risk of bias exists. Electric pulp test (EPT) sensitivity threshold during active OTM was increased by 4.25 SD (P < 0.001) and the relative risk (RR) of pulpal non-sensitivity was 13.27 (P < 0.001) higher compared to pre-orthodontic baseline status. Significant differences were between subgroups associated with the type of OTM. A positive relationship between pulpal non-sensitivity and mean patient age was discovered (P = 0.041). After OTM the risk of pulpal non-sensitivity remained 5.76 times higher (P < 0.001) in the long term. Conclusions: Evidence showed that OTM could affect dental pulp sensitivity. The type of OTM and patients' age were identified as clinically relevant risk factors. Clinical significance: Orthodontic tooth movement negatively impacts the sensitivity of dental pulp during active treatment and to a lesser degree in the long term. Pulpal sensitivity tests during active OTM should therefore be interpreted with caution. Data indicates younger patients have a lower risk of negative pulpal sensitivity during orthodontic treatment.

Three-dimensional evaluation of the association between face and back asymmetry among pre-pubertal subjects.

AIM: The aim was to compare the degree of back symmetry in two groups of subjects with and without pathologic facial asymmetry and to assess any possible associations between face and back asymmetry evaluated on three-dimensional surface face and back scans. MATERIALS AND METHODS: The study design consisted of allocation of 70 subjects (35 females, 35 males) aged 6.4±0.5 years, according to the percentage of whole face symmetry assessed on three-dimensional (3D) facial scans into a 'symmetric' (symG; symmetry ≥70%) and 'asymmetric'(asymG; symmetry <70%). The 3D face and back scans were analysed using colour deviation maps and percentages of symmetry of the whole face and back surfaces as well as their three separate areas: forehead, maxillary and mandibular areas for the face and neck, upper and middle trunk areas for the back, were calculated. Non-parametric statistical tests were used for between-group comparisons (Mann-Whitney U test). Within each group, differences between each face or back area were tested with the Friedman test. Correlations between face and back symmetry were assessed with the Spearman rho coefficient. RESULTS: The symG exhibited a significantly higher symmetry in each facial area than the asymG. The mandibular area was the least symmetric area of the face within each group, with significantly smaller values than the maxillary area in the symG and significantly smaller values than the forehead and maxillary area in the asymG. The percentage of whole back symmetry did not significantly differ (p>0.05) between the symG ( 82.00% [67.4;88.00]) and asymG (74.3% [66.1;79.6]). The only significant between-group difference was observed for the symmetry of the upper trunk area (p=0.021), with lower symmetry values in the asymG. No significant associations were detected between face and back parameters. CONCLUSION: The percentages of symmetry in each facial area were significantly higher among subjects without pathologic facial asymmetry. The most asymmetric area of the face, regardless of the degree of whole face symmetry, was its mandibular area. No significant differences were detected within different back areas; however, subjects with asymmetric faces showed significantly smaller symmetry of their upper trunk area.

Assessment of facial asymmetry in growing subjects with a three-dimensional laser scanning system.

OBJECTIVES: To evaluate facial asymmetry in growing subjects with no malocclusion on three-dimensional laser facial scans. SETTING AND SAMPLE POPULATION: Twenty-seven healthy Caucasian children (15 boys and 12 girls, aged 5.4 ± 0.3 years) in the primary dentition without malocclusion were randomly selected from a local kindergarten in Slovenia. MATERIAL AND METHODS: Surface facial images were obtained using a three-dimensional laser scanning system at baseline and at 18, 30, 42 and 54 months of follow-up. Facial asymmetry was assessed quantitatively by measuring the average distance between facial image and mirrored image. Further, the percentage of asymmetry was calculated as the percentage of image to mirrored image not coinciding within 0.5 mm. Qualitative assessment was performed on colour deviation maps by recording the predominant side of the face for the upper, middle and lower parts of the face separately. Nonparametric tests were used for data analysis. RESULTS: No face was perfectly symmetric. The average distance between the mirrored images for the whole face ranged 0.22-0.85 mm and the percentage of asymmetry 7.8-66.9. There were no significant gender differences (p > 0.05), and no significant change was found over the observed period. The upper part of the face was the least asymmetric, while the lower and middle parts showed similar degrees of asymmetry. CONCLUSION: Facial asymmetry is already present at an early developmental stage and does not show any tendency to increase or decrease with growth in the pre-pubertal period.