1.
Immunol Lett
; 90(2-3): 161-3, 2003 Dec 15.
Article
in English
| MEDLINE
| ID: mdl-14687719
ABSTRACT
A vaccinia virus recombinant containing the non-structural tick-borne encephalitis virus (TBEV) NS1 gene was developed. The recombinant expressed native dimeric form of the NS1 protein in infected cells and protected mice against lethal infection with TBEV.
Subject(s)
Encephalitis Viruses, Tick-Borne/immunology , Encephalitis, Tick-Borne/immunology , Encephalitis, Tick-Borne/prevention & control , Vaccinia virus/genetics , Viral Nonstructural Proteins/immunology , Animals , Antibodies, Viral/immunology , Cell Line , Encephalitis Viruses, Tick-Borne/genetics , Encephalitis, Tick-Borne/virology , Mice , Mice, Inbred BALB C , Radioimmunoprecipitation Assay , Survival Rate , Viral Nonstructural Proteins/genetics , Viral Vaccines/immunology
2.
Acta Virol
; 25(2): 95-100, 1981 Mar.
Article
in English
| MEDLINE
| ID: mdl-6166186
ABSTRACT
Chronic infection of L cells with Sindbis virus, induced in the absence of antiviral antibody, was studied by virological methods in combination with light and electron microscopy. Both Sindbis virus and endogenous oncovirus antigens were revealed in the cells by immunofluorescence. Sindbis virus and interferon were detected in the culture fluid. Immunoelectron microscopy revealed aggregation of Sindbis virus particles by immune serum.
